Mortality in patients with paravalvular abscess diagnosed by transesophageal echocardiography

Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography
John E CosmiItzhak Kronzon

Abstract

Paravalvular abscess is a complication of endocarditis that may lead to persistent infection, conduction abnormalities, fistula formation, worsening congestive heart failure, and death. Between 1991 and 2001, paravalvular abscess was identified on transesophageal echocardiography in 24 patients who subsequently underwent surgical treatment. Echocardiographic findings were reviewed for location of abscess, presence of a valvular prosthesis, valvular function, and presence of vegetations. Information gathered included the time interval between transesophageal echocardiography diagnosis and operation, inhospital mortality, and microbiologic data. Of 24 patients, 9 died, for a mortality of 38%. Of the patients who died, the average survival after operation was 43 days, with a range of 1 to 238 days. Of the 14 patients with significant valvular or paravalvular regurgitation, 8 died (57%). However, of the 10 patients with mild or no regurgitation, only 1 died (10%). This difference was statistically significant (P =.02). Patients without preserved valve function (those with moderate or severe regurgitation) have a significantly worse outcome (57% mortality) than do those with normal valvular function (10% mortality).

References

Mar 21, 1991·The New England Journal of Medicine·W G DanielP R Lichtlen
Jan 1, 1989·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·J W CooperP Fan

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Citations

Nov 19, 2013·BMC Infectious Diseases·Laurenzia FerrarisSpinello Antinori
Feb 22, 2007·Journal of Cardiovascular Medicine·Roberto MocchegianiMaura Nataloni
Feb 16, 2010·Journal of Cardiovascular Medicine·Maura NataloniRoberto Mocchegiani
Apr 7, 2010·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Randolph P Martin
Dec 17, 2009·Clinical Cardiology·Khaled BachourLuis Afonso
Dec 27, 2005·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Tasneem Z NaqviRobert J Siegel
Jul 14, 2017·A & a Case Reports·Natalie A SilvertonCandice K Morrissey
Oct 27, 2017·Current Cardiology Reports·Luis AfonsoAnirudh Penumetcha
Apr 26, 2021·Cardiology Clinics·Takeshi KitaiYutaka Furukawa

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