Mortality risk for women on chronic hemodialysis differs by age

Canadian Journal of Kidney Health and Disease
Manish M SoodNavdeep Tangri

Abstract

Previous reports have demonstrated similar survival for men and women on hemodialysis, despite women's increased survival in the general population. To examine the effect of age on mortality in women undergoing chronic hemodialysis. A retrospective cohort study using an administrative data registry, the Canadian Organ Replacement Registry (CORR) from Jan. 2001 and Dec. 2009. Canada. 28,971 (Women 11,792 (40.7%), Men 17,179 (59.3%)) incident chronic hemodialysis patients who survived greater than 90 days on dialysis. All-cause mortality. Cox proportional hazards and competing risks models were employed to determine the independent association between sex, age and likelihood of all-cause mortality with renal transplantation as the competing outcome. During the study period, 6060 (51.4%) of women and 8650 (50.4%) of men initiating dialysis died. Younger women experienced higher mortality (Age < 45: Women 22.5%, Men 18.2%, hazard ratio (HR) 1.31 (1.12-1.52)) whereas elderly women experience lower mortality (Age 75-85: Women 65%, Men 67.3%, HR 0.94 95% CI 0.88-0.99, Age > 85: Women 66%, Men 70.2%, HR 0.83 95% CI 0.71-0.97) compared to men. This relationship persisted after accounting for the competing risk of transplantation. The ca...Continue Reading

References

Nov 1, 1994·Journal of the American Society of Nephrology : JASN·W E BloembergenR A Wolfe
May 29, 1999·Statistical Methods in Medical Research·J L Schafer
Nov 30, 2000·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·B C AstorM J Klag
Jul 26, 2002·Journal of the American Society of Nephrology : JASN·Donal ReddanUNKNOWN National ESRD CPM Work Group
Dec 11, 2002·Kidney International·Christopher D MillerMichael Allon
Feb 25, 2003·JAMA : the Journal of the American Medical Association·Ashwini R Sehgal
Jul 31, 2004·Journal of the American Society of Nephrology : JASN·Geoffrey A BlockGlenn M Chertow
Mar 25, 2005·Journal of the American Society of Nephrology : JASN·Brad C AstorUNKNOWN CHOICE Study
Jun 22, 2007·Journal of the American Society of Nephrology : JASN·Emmanuel VillarRené Ecochard
Apr 29, 2008·American Heart Journal·John T NguyenRussell V Luepker
Jan 9, 2009·Journal of the American Society of Nephrology : JASN·Dorry L SegevRobert A Montgomery
Sep 14, 2010·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Kitty J JagerFriedo W Dekker
Nov 10, 2010·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Marion VerduijnSaskia le Cessie
Jan 25, 2011·Clinical Journal of the American Society of Nephrology : CJASN·Louise M MoistBrenda R Hemmelgarn
Mar 17, 2011·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Wang XiLouise M Moist
Jul 8, 2011·Clinical Journal of the American Society of Nephrology : CJASN·Juan J CarreroKitty J Jager
Aug 11, 2011·JAMA : the Journal of the American Medical Association·Lauren M KucirkaDorry L Segev

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Citations

Oct 28, 2019·Clinical Journal of the American Society of Nephrology : CJASN·Laurie A Tomlinson, Catherine M Clase
Feb 4, 2021·International Journal of Environmental Research and Public Health·Natalino Salgado FilhoRicardo de Castro Cintra Sesso

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Methods Mentioned

BETA
coronary artery bypass
Replacement Registry

Software Mentioned

R
PASW

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