Mortality risks for all causes and cardiovascular diseases and reduced GFR in a middle-aged working population in Taiwan

American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation
Ting-Yuan David ChengChi Pang Wen

Abstract

Effects of decreased estimated glomerular filtration rate (eGFR) on cardiovascular disease (CVD) mortality are uncertain in Chinese general populations. Prospective cohort study. 17,026 adults 50 years and older in Taiwan. A subset of 7,968 had repeated measurements. Decreased eGFR and its progression. eGFR was calculated from serum creatinine level by using the Modification of Diet in Renal Disease Study equation. Mortality from all causes and CVD, including coronary heart disease (CHD) and stroke, from the National Death Registry. Hazard ratios (HRs) and Kaplan-Meier survival curves were calculated for participants with a moderate to severe decrease in eGFR (<60 mL/min/1.73 m(2)) compared with those with normal eGFR (> or =90 mL/min/1.73 m(2)). HR of a rapid decrease (> or =20%) in eGFR was also calculated. Mean age of all participants was 57.2 +/- 5.2 (SD) years. We observed 1,682 deaths in 15 years of follow-up. Participants with a moderate to severe decrease in eGFR had increased HRs for mortality from all causes (1.44; 95% confidence interval [CI], 1.22 to 1.70), CVD (1.90; 95% CI, 1.36 to 2.65), CHD (2.07; 95% CI, 1.26 to 3.41), and stroke (2.16; 95% CI, 1.29 to 3.62) after adjusting for confounders. Decreased eGFR was a...Continue Reading

References

Jan 24, 1998·JAMA : the Journal of the American Medical Association·G HowardG S Tell
May 19, 2000·International Journal of Epidemiology·T H LuM C Chou
Jul 8, 2000·Stroke; a Journal of Cerebral Circulation·T EngstadM Viitanen
Jul 25, 2000·Circulation·B H Lorell, B A Carabello
Nov 17, 2001·Asia Pacific Journal of Clinical Nutrition·G L Khor
Feb 22, 2002·Journal of the American Society of Nephrology : JASN·Paul MuntnerPaul K Whelton
Sep 18, 2002·Kidney International·Ronald M A HenryCoen D A Stehouwer
Sep 27, 2002·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Esther M BrigantiRobert C Atkins
Dec 25, 2002·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Josef CoreshAndrew S Levey
Feb 7, 2003·Journal of the American College of Cardiology·Guruprasad ManjunathMark J Sarnak
Mar 13, 2003·Kidney International·Guruprasad ManjunathMark J Sarnak
May 10, 2003·Stroke; a Journal of Cerebral Circulation·Thomas TruelsenUNKNOWN WHO MONICA Project
Oct 29, 2003·Circulation·Mark J SarnakUNKNOWN American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology,
Nov 8, 2003·Hypertension·Mark J SarnakUNKNOWN American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology,
Feb 19, 2004·JAMA : the Journal of the American Medical Association·Caroline S FoxDaniel Levy
Apr 22, 2004·Journal of the American Society of Nephrology : JASN·Daniel E WeinerMark J Sarnak
Apr 28, 2004·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Brad C AstorJosef Coresh
Jun 24, 2004·Journal of the American Society of Nephrology : JASN·Eric L KnightGary C Curhan
Sep 24, 2004·The New England Journal of Medicine·Alan S GoChi-yuan Hsu
Mar 9, 2005·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Li ZuoHai-Yan Wang
May 20, 2005·The New England Journal of Medicine·Michael G ShlipakCatherine Stehman-Breen
Jun 16, 2005·Kidney International·Marcello TonelliUNKNOWN Cholesterol and Recurrent Events (CARE) Trial Investigators
Sep 16, 2005·The New England Journal of Medicine·Jiang HePaul K Whelton
Oct 27, 2005·Diabetes Care·Chi Pang WenShu Li Wang
Dec 14, 2005·Archives of Internal Medicine·Jasper J BrugtsJacqueline C M Witteman
Jun 9, 2006·The New England Journal of Medicine·Lesley A StevensAndrew S Levey
Jul 26, 2006·Circulation Journal : Official Journal of the Japanese Circulation Society·Koshi NakamuraUNKNOWN NIPPON DATA90 Research Group
Aug 4, 2006·Journal of the American Society of Nephrology : JASN·Luxia ZhangHaiyan Wang
Aug 26, 2006·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Daniel E WeinerMark J Sarnak
Sep 22, 2006·Journal of the American Society of Nephrology : JASN·Ying-Chun MaHai-Yan Wang
Oct 25, 2006·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Chih-Cheng HsuWu-Chang Yang
Jan 11, 2007·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·LuXia ZhangHaiYan Wang
Jan 12, 2007·Journal of the American Society of Nephrology : JASN·Keattiyoat WattanakitBeth D Weatherley
Mar 9, 2007·Journal of the American Society of Nephrology : JASN·Anna KottgenJosef Coresh

❮ Previous
Next ❯

Citations

Aug 18, 2010·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Michael P QuinnDamian G Fogarty
Jul 6, 2012·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Tanvir Chowdhury TurinBrenda R Hemmelgarn
Oct 5, 2010·BMJ : British Medical Journal·Meng LeeBruce Ovbiagele
Nov 7, 2009·Journal of the American Society of Nephrology : JASN·Kunihiro MatsushitaJosef Coresh
Dec 5, 2009·World Journal of Gastroenterology : WJG·Yu-Cheng LinPau-Chung Chen
Nov 30, 2013·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Paola RucciUNKNOWN Prevention of Renal Insufficiency Progression (PIRP) Project
Jan 25, 2013·Kidney International·Tanvir C TurinBrenda R Hemmelgarn
Mar 30, 2013·Kidney International·Jain Nishank, S Susan Hedayati
Dec 11, 2014·Kidney International·Mathias GorskiCarsten A Böger
Jan 6, 2016·Clinical and Experimental Nephrology·Badrul Munir SohelMohammad Al Mamun
Oct 11, 2015·International Journal of Cardiology·Tanvir C TurinBrenda R Hemmelgarn
Jan 15, 2013·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·O MoranneC Mariat
Feb 25, 2011·Clinica Chimica Acta; International Journal of Clinical Chemistry·Vin-Cent WuUNKNOWN TAIPAI Study Group
Dec 12, 2012·International Journal of Cardiology·Martin J HolzmannUlrik Sartipy
May 21, 2016·Clinical Journal of the American Society of Nephrology : CJASN·Tazeen H JafarNish Chaturvedi
Jun 18, 2016·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Chava L RamspekUNKNOWN NECOSAD Study Group
Dec 15, 2015·Journal of the American Society of Nephrology : JASN·Csaba P KovesdyUNKNOWN CKD Prognosis Consortium
Dec 15, 2015·Journal of the American Society of Nephrology : JASN·David M J NaimarkUNKNOWN CKD Prognosis Consortium
Feb 17, 2017·International Journal of Epidemiology·Xifeng WuChi Pang Wen
Sep 13, 2014·Journal of the American Heart Association·Tanvir Chowdhury TurinBrenda R Hemmelgarn
Jul 26, 2011·Clinical Journal of the American Society of Nephrology : CJASN·Tanvir Chowdhury Turin, Brenda R Hemmelgarn
Sep 29, 2019·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·A FieldingA T Stearns
Feb 11, 2011·Expert Review of Neurotherapeutics·Meng Lee, Bruce Ovbiagele
Jun 16, 2012·American Journal of Nephrology·Tanvir Chowdhury TurinBrenda R Hemmelgarn
Jun 4, 2020·Surgery Today·Masanori SandoMasato Nagino

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atherosclerosis Disease Progression

Atherosclerosis is the buildup of plaque on artery walls, causing stenosis which can eventually lead to clinically apparent cardiovascular disease. Find the latest research on atherosclerosis disease progression here.

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

Brain Ischemia

Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. Discover the latest research on brain ischemia here.

Related Papers

Clinical Journal of the American Society of Nephrology : CJASN
Robert M PerkinsTaher Yahya
Journal of the American Society of Nephrology : JASN
Kunihiro MatsushitaJosef Coresh
Journal of the American Society of Nephrology : JASN
Ziyad Al-AlySeth Eisen
© 2022 Meta ULC. All rights reserved