Mosquito larvicidal activity of active constituent derived from Chamaecyparis obtusa leaves against 3 mosquito species

Journal of the American Mosquito Control Association
Young-Su JangHoi-Seon Lee

Abstract

Mosqutio larvicidal activity of Chamaecyparis obtusa leaf-derived materials against the 4th-stage larvae of Aedes aegypti (L.), Ochlerotatus togoi (Theobald), and Culex pipiens pallens (Coquillett) was examined in the laboratory. A crude methanol extract of C. obtusa leaves was found to be active (percent mortality rough) against the 3 species larvae; the hexane fraction of the methanol extract showed a strong larvicidal activity (100% mortality) at 100 ppm. The bioactive component in the C. obtusa leaf extract was characterized as beta-thujaplicin by spectroscopic analyses. The LC50 value of beta-thujaplicin was 2.91, 2.60, and 1.33 ppm against Ae. aegypti, Oc. togoi, and Cx. pipiens pallens larvae. This naturally occurring C. obtusa leaves-derived compound merits further study as a potential mosquito larval control agent or lead compound.

References

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Nov 24, 1998·Medical and Veterinary Entomology·F ChandreP Guillet
Jun 13, 2002·Journal of Agricultural and Food Chemistry·Young-Cheol YangHoi-Seon Lee
Dec 11, 2003·Journal of Agricultural and Food Chemistry·Young-Cheol YangHoi-Seon Lee
Mar 17, 2005·Journal of Agricultural and Food Chemistry·Young-Su JangHoi-Seon Lee

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Citations

Jan 8, 2008·Parasitology Research·A Abdul RahumanKannappan Geetha
Aug 9, 2008·Parasitology Research·A Abdul RahumanGeetha Gopalakrishnan
Dec 24, 2015·Journal of Physiological Anthropology·Harumi IkeiYoshifumi Miyazaki
Jun 6, 2016·Neurotoxicology·Nicholas R LarsonJeffrey R Bloomquist
Feb 19, 2015·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Yaping LiangMingshan Ji
May 10, 2020·Environmental Science and Pollution Research International·Dinesh KumarVeena Agrawal
Oct 18, 2007·Journal of the American Mosquito Control Association·Helen SpaffordPhil Weinstein

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Methods Mentioned

BETA
column chromatography

Software Mentioned

SAS

Related Concepts

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