Mosquito proboscis-inspired needle insertion to reduce tissue deformation and organ displacement.

Scientific Reports
Annie D R LiAlbert J Shih

Abstract

This study investigates mosquito proboscis-inspired (MPI) insertion applied to the clinically used biopsy needle to reduce tissue deformation and organ displacement. Advanced medical imagining has enabled early-stage identification of cancerous lesions that require needle biopsy for minimally invasive tissue sampling and pathological analysis. Accurate cancer diagnosis depends on the accuracy of needle deployment to the targeted cancerous lesion site. However, currently available needle delivery systems deform and move soft tissue and organs, leading to a non-diagnostic biopsy or undersampling of the target. Two features inspired by the mosquito proboscis were adopted for MPI insertion in prostate biopsy: (1) the harpoon-shape notches at the needle tip and (2) reciprocating needle-cannula motions for incremental insertion. The local tissue deformation and global prostate displacement during the MPI vs. traditional direct insertions were quantified by optically tracking the displacement of particle-embedded tissue-mimicking phantoms. Results show that the MPI needle insertion reduced both local tissue deformation and global prostate displacement because of the opposite needle-cannula motions and notches which stabilized and redu...Continue Reading

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Mar 17, 2020·Journal of the Mechanical Behavior of Biomedical Materials·Annie D R LiAlbert Shih

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Methods Mentioned

BETA
biopsy
force measurement

Software Mentioned

Moog Animatics
MRF
Ncorr
TB
MATLAB

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