Mosquito repellency of the seeds of celery (Apium graveolens L.)

Annals of Tropical Medicine and Parasitology
B TuetunB Pitasawat

Abstract

When the mosquito repellencies of four fractions of Apium graveolens seeds (one hexane, two dichloromethane and one methanolic) were investigated in the laboratory, all four were found to offer human volunteers some protection against female, adult Aedes aegypti. The hexane fraction, however, was found to exhibit the highest repellency in the laboratory, with median effective doses (ED50) and ED95 of 0.41 and 2.93 mg/cm2 skin, respectively. Only this fraction, which was also found to provide protection against mosquito bites for 3.5 h when applied, in the laboratory, at a concentration of 250 mg/ml, was then investigated for its repellency in the field and its stability. In storage, it was found to retain its repellency for at least 2 months, although significant reductions in its repellency were observed (in terms of shortened complete-protection times) after 3 months, whatever the temperature of storage (-20 degrees C, 4 degrees C, or room temperature). When applied to the skin of volunteers under field conditions, the hexane fraction showed strong repellent activity against a wide range of mosquito species belonging to various genera (Ae. gardnerii, Ae. lineatopennis, Armigeres subalbatus, Culex tritaeniorhynchus, Cx. vishnu...Continue Reading

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Citations

Aug 7, 2010·Parasitology Research·Chinnaperumal KamarajGandhi Elango
Dec 8, 2010·Parasitology Research·Gandhi ElangoAbdul Abduz Zahir
Nov 2, 2011·Parasitology Research·Rajan Maheswaran, Savarimuthu Ignacimuthu
Apr 18, 2013·Journal of Natural Medicines·Siti Latifah Abd KadirRazauden Mohamed Zulkifli
Nov 10, 2013·Travel Medicine and Infectious Disease·Eleonora LupiPatricia Schlagenhauf
Oct 11, 2014·Parasitology Research·Kaliyan VeerakumarS L Hoti
Nov 3, 2005·Tropical Medicine & International Health : TM & IH·Benjawan TuetunBenjawan Pitasawat

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