PMID: 9193148Jan 1, 1997Paper

Mossy-fibre sensory input to the cerebellum

Progress in Brain Research
M Glickstein

Abstract

The role of the spinal and vestibular afferents to the cerebellum in the control of movement first began to be recognized towards the end of the 19th century. By the middle of the present century it was clear that visual and auditory information are also relayed to the cerebellum from the cerebral cortex and brainstem by way of the pontine nuclei. Pontine cells project to the cerebellar cortex where they terminate as mossy fibres. The corticopontine projection arises from cells in lamina V of the cerebral cortex. Cells in the rat primary somatosensory cortex also provide an input to the basal ganglia, but the two populations are largely segregated in distinct sub-laminae. In monkeys, and probably in humans, the cortical visual input to the pontine nuclei arises from the dorsal stream of extrastriate visual areas. Experimental and clinical evidence suggest that damage to this pathway at the cortical level, or interruption of its corticopontine fibres within the internal capsule produce profound disturbance in visuomotor guidance. One of the major pathways through the brain for the visual guidance of movement is relayed from the dorsal stream of extrastriate areas to the cerebellum by way of the pontine nuclei.

Citations

Nov 28, 2002·The European Journal of Neuroscience·Irving M RetiJay M Baraban
Jun 28, 2006·The Journal of Comparative Neurology·Mercedes PeralesJorge J Prieto
Jun 7, 2005·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Stewart Shipp
Apr 3, 2019·Annual Review of Neuroscience·Jeremy D SchmahmannMark A Halko
Oct 16, 2015·Journal of Neurophysiology·Saeka TomatsuShinji Kakei
Jul 20, 2001·Molecular and Cellular Neurosciences·M GesemannD D O'Leary
Jul 12, 2020·Neuroscience·Ayesha R ThanawallaEiman Azim

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