Mother-to-child transmission and gestational syphilis: Spatial-temporal epidemiology and demographics in a Brazilian region

PLoS Neglected Tropical Diseases
Joyce Marinho de SouzaMarcus Vinícius Pimenta Rodrigues

Abstract

Syphilis is a Sexually Transmitted Infection (IST) with significant importance to public health, due to its impact during pregnancy (Gestational Syphilis-GS); especially because syphilis can affect fetus and neonates' development (mother-to-child transmission-MTCT of syphilis), by increasing susceptibility to abortion, premature birth, skeletal malformations, meningitis and pneumonia. Measures to control and eliminate MTCT of syphilis have failed on the last few years in Brazil and this research aimed to identify the seasonality of notified cases of syphilis in a region of São Paulo state. The studied region, Pontal do Paranapanema, comprises 32 cities located in the West of São Paulo state, in Brazil. Data collected from the National System of Aggravations and Notification (SINAN) website was used to calculate the incidence rate of GS and MTCT. The incidence rate of GS was acquired dividing number of cases by number of women in each municipality and MTCT using number of live births in each year (from 2007 to 2013) in each municipality. This result was then, standardized multiplying incidence rate by 10,000 and expressed as incidence/10,000 women or live births, for GS and MTCT, respectively. To identify possible endemic/epidem...Continue Reading

References

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Citations

Apr 10, 2020·PloS One·Marquiony Marques Dos SantosKenio Costa de Lima
Aug 16, 2019·Environmental Research·Joanna A RuszkiewiczMichael Aschner
Jan 14, 2022·Scientific Reports·Joelma Alexandra Ruberti MedeirosFrancisco Chiaravalloti-Neto

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Software Mentioned

Geographic Information System software ( GIS )
SINAN
DATASUS
R
IBGE

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