PMID: 8584359Nov 1, 1995Paper

Mother-to-child transmission of human immunodeficiency virus type 1 and type 2 and dual infection: a cohort study in Banfora, Burkina Faso

The Pediatric Infectious Disease Journal
T PrazuckJ E Malkin

Abstract

A prospective cohort study on the mother-to-child transmission of human immunodeficiency virus type 1 (HIV1), type 2 (HIV2) and dual positivity (HIV1 + HIV2) was carried out in Banfora, West Burkina Faso. The study samples consist of 117 newborns of HIV-seropositive women matched to 234 newborns of HIV-seronegative women. Among cases, 91 were born of HIV1-seropositive mothers, 15 were born of HIV2-seropositive mothers and 11 were born of HIV1 and HIV2 dual-seropositive mothers and were included in an 18-month follow-up. Calculation of the mother-to-child transmission rate was according to the recommendations of the European Economic Community working group. The HIV1 mother-to-child transmission rate was estimated to be 27.8% (95% confidence interval (CI) 24.5 to 32.4) with one method and 25.5% (95% CI 13.5 to 37.5) with a second method. For HIV2, this rate was estimated to be 29.5% (95% CI 26.0 to 39.8) and was not statistically different from the HIV1 mother-to-child transmission rate. No case of transmission was observed in children born of dual seropositive mothers. Survival rate at month 18 was significantly lower for children born of HIV1 mothers: 83.7% (95% CI 78.2 to 92.2). Survival rates were similar between children bo...Continue Reading

Citations

Aug 1, 2006·Epidemiology·Adam RothPeter Aaby
Apr 20, 2018·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Selly BaUNKNOWN University of Washington–Dakar HIV-2 Study Group
Nov 4, 2000·Clinical and Diagnostic Laboratory Immunology·R KannangaiG Sridharan
Jan 22, 2005·International Journal of Epidemiology·Adam RothPeter Aaby

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