PMID: 9181348Jan 1, 1996Paper

Motion-onset visual evoked potentials improve the diagnosis of glaucoma

Documenta Ophthalmologica. Advances in Ophthalmology
Z KubováJ Svĕrák

Abstract

Chronic glaucoma has been shown preferentially to damage larger retinal cells and optic nerve fibres that provide the input to the magnocellular visual pathway. We compared the motion-onset visual evoked potentials (primarily the magnocellular system) with those to standard pattern reversal in 20 patients with bilateral chronic glaucoma. For motion-onset visual evoked potentials, the pattern (isolated 40' checks of 10% contrast) moved in four cardinal directions (varied randomly from trial to trial) at a velocity of 10 deg/s for 20 ms, with an interstimulus interval of 1 s. In pattern-reversal stimulation, the checkerboard reversed at a rate of 2 reversals per second. In 60% of the eyes investigated, the results of both types of visual evoked potentials correlated, showing either normal (27.5%) or increased (32.5%) latencies. In the remaining 40% of the eyes, the normal pattern-reversal visual evoked potential latencies were accompanied by prolonged motion-onset visual evoked potentials. The high occurrence of delayed motion-onset visual evoked potentials in our patients confirms the primary magnocellular loss in chronic glaucoma and suggests that the motion-onset VEPs are suitable for detection of glaucomatous changes.

References

Nov 1, 1977·Journal of the Optical Society of America·D Regan
Jan 1, 1992·Documenta Ophthalmologica. Advances in Ophthalmology·Z Kubová, M Kuba
Jan 1, 1992·Documenta Ophthalmologica. Advances in Ophthalmology·M Kuba, Z Kubová
Mar 1, 1991·Electroencephalography and Clinical Neurophysiology·S TobimatsuM Kato
Feb 1, 1995·The British Journal of Ophthalmology·K A BaezR A Hitchings
Jan 1, 1995·Vision Research·Z KubováC Blakemore
Apr 1, 1994·Acta Ophthalmologica·F J Fernández-TiradoF M Honrubia

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Citations

Apr 14, 2007·Documenta Ophthalmologica. Advances in Ophthalmology·Sven P Heinrich
Feb 25, 2014·Documenta Ophthalmologica. Advances in Ophthalmology·Zuzana KubovaMarie Chutna
Apr 2, 2015·Indian Journal of Ophthalmology·Inmaculada CabezosVicente Camps
Apr 17, 2012·Vision Research·Miroslav KubaFrantišek Vít
Nov 30, 2006·Vision Research·M KubaJ Langrová
Oct 4, 2006·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Zuzana KubováKarel Honegr

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