PMID: 7543942Apr 1, 1995Paper

Motoneuron properties after operantly conditioned increase in primate H-reflex

Journal of Neurophysiology
J S Carp, Jonathan R Wolpaw

Abstract

1. Monkeys can increase (HRup conditioning mode) or decrease (HRdown conditioning mode) the triceps surae (TS) H-reflex in response to an operant conditioning task. This conditioning modifies the spinal cord. To define this spinal cord plasticity and its role in the behavioral change (H-reflex increase or decrease), we have recorded intracellularly from TS motoneurons in conditioned animals. The present report describes data from HRup animals and compares them with data from previously studied naive (NV; i.e., unconditioned) animals. 2. Thirteen monkeys (Macaca nemestrina, male, 3.8-7.1 kg) were exposed to the HRup conditioning mode, in which reward occurred when H-reflex size in one leg (i.e., the trained leg) was above a criterion value. Conditioning was successful (i.e., increase of > or = 20%) in 12 of the 13 animals. At the end of conditioning, H-reflex size in the trained leg averaged 188% of its initial value, whereas size in the control leg averaged 134% of its initial value. 3. Intracellular recordings were obtained from 136 TS motoneurons on trained (UT + motoneurons) and control (UC + motoneurons) sides of the successful animals. Measurements included axonal conduction velocity, input resistance, time constant, elect...Continue Reading

Citations

Aug 25, 2001·Annual Review of Neuroscience·J R Wolpaw, A M Tennissen
Jan 20, 2006·The European Journal of Neuroscience·Yu WangXiang Yang Chen
Jun 30, 2006·Journal of Neurophysiology·Xiang Yang ChenJonathan R Wolpaw
Jul 1, 2006·Journal of Applied Physiology·E Paul Zehr
Mar 31, 1999·Journal of Neurotrauma·X Y ChenB T Stokes
Oct 8, 1999·Journal of Neurotrauma·G D Muir
Dec 1, 1996·Journal of Neurotrauma·X Y ChenB T Stokes
Feb 9, 2005·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Gary Kamen, Christopher A Knight
Aug 25, 2007·Behavioral and Cognitive Neuroscience Reviews·Jonathan R Wolpaw
Jul 14, 2006·Journal of Neurophysiology·Jonathan S CarpJonathan R Wolpaw
Jul 16, 2010·Annals of the New York Academy of Sciences·Xiang Yang ChenJonathan R Wolpaw
Jan 3, 2013·Muscle & Nerve·Aiko K ThompsonJonathan R Wolpaw
Dec 10, 1999·Medicine and Science in Sports and Exercise·B LeongJ R Burke
Aug 15, 2003·Journal of Neurophysiology·Xiang Yang ChenJonathan R Wolpaw
Feb 5, 2002·Journal of Neurophysiology·Xiang Yang Chen, Jonathan R Wolpaw
May 25, 2007·Journal of Neurophysiology·Xiang Yang ChenJonathan R Wolpaw
Jul 29, 2008·The European Journal of Neuroscience·Shreejith PillaiXiang Yang Chen
Sep 9, 2006·Journal of Applied Physiology·DeAnna L AdkinsJeffrey A Kleim
Jul 14, 2020·Exercise and Sport Sciences Reviews·Per AagaardJesper Lundbye-Jensen
Jun 17, 2006·Journal of Applied Physiology·P GardinerC J Heckman
Nov 23, 2006·Journal of Neurotrauma·Xiang Yang ChenJonathan R Wolpaw
Sep 1, 2005·Canadian Journal of Applied Physiology = Revue Canadienne De Physiologie Appliquée·Gary Kamen
Aug 18, 2012·Neural Plasticity·Behdad Tahayori, David M Koceja
Mar 29, 2014·Frontiers in Integrative Neuroscience·Aiko K Thompson, Jonathan R Wolpaw
Feb 5, 2013·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Richard B SteinMaryam Soleimani
Oct 5, 2010·The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry·Jonathan R Wolpaw
Jun 28, 2001·Brain Research Bulletin·G Székely
May 2, 2006·Progress in Neurobiology·Jonathan R Wolpaw, Jonathan S Carp
Jun 3, 2005·Learning & Memory·Xiang Yang Chen, Jonathan R Wolpaw

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