PMID: 8938361Feb 1, 1996Paper

Motor activity of refashioned colorectoanus in patients with total colonic aganglionosis

Journal of Pediatric Surgery
M EndoM Kitajima

Abstract

An ano-recto-sigmoid colon pressure study was designed to evaluate the characteristics of the motor activity of refashioned colorectoanus in patients with total colonic aganglionosis (TCA) in comparison to patients with rectosigmoid Hirschsprung's disease (HD) and healthy children (HC), and to elucidate the pathophysiology of the pulled-through ileum, with aganglionic colon as an onlay patch, in coordination with the anal sphincter. The study group consisted of six patients with TCA, six with HD who underwent endorectal colonic pull-through, and six HC. Pressure studies were performed using a triple-lumen catheter; recording sites were 15 and 9 cm from the anal verge, and at the anal canal. The following were measured and compared: (1) anal canal pressure profile, (2) resting pattern of activity at the refashioned colorectum and anal canal, and (3) changes in motor activity after stimulation with cold water and glycerin. The motor activities of the refashioned colorectoanus of TCA and HD patients differed greatly from those of HC. All six HC had no isolated high-amplitude contraction (IHAC) in the colorectum during the 45-minute study period; they complained of a strong urge to defecate after glycerin enema and actually did so....Continue Reading

References

Mar 1, 1992·Journal of Pediatric Surgery·M Levy, M Reynolds
Aug 1, 1988·Journal of Pediatric Surgery·M N RossP Clevenger
Jun 1, 1981·Journal of Pediatric Surgery·P K KottmeierD H Klotz
Oct 1, 1994·Journal of Pediatric Surgery·M EndoJ Yokoyama

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