Motor and Sensory Cortical Changes after Contralateral Cervical Seventh Nerve Root (CC7) Transfer in Patients with Brachial Plexus Injuries

The Journal of Hand Surgery Asian-Pacific Volume
Ryosuke KakinokiMasao Akagi

Abstract

Previous animal studies demonstrated that the sensory and motor functions in ipsilesional upper limbs that had been reconstructed by CC7 transfer eventually associated with the contralesional brain cortices that had originally mediated the functions of the ipsilesional upper limbs before brachial plexus injury (BPI). Our hypothesis was that the same findings would be seen in humans. Four patients with total BPI treated with CC7 transfer were included. Changes in the locations of the activated areas in the primary motor (M1) and somatosensory (S1) cortices corresponding to the motor outputs to and sensory inputs from the ipsilesional limbs were investigated using functional near-infrared spectroscopy (fNIRS) 2-3 years and 6-7 years after surgery. One patient was excluded from the evaluation of motor function after CC7 transfer. The motor and sensory functions of the ipsilesional upper limb in all patients were still controlled by the ipsilesional brain hemisphere 2-3 years after CC7 transfer. The reconstructed motions of the ipsilesional upper limbs correlated with the contralesional M1 in one patient and the bilateral M1s in another patient (both of whom demonstrated good motor recovery in the ipsilesional upper limbs) and with...Continue Reading

References

Oct 1, 1992·The Journal of Hand Surgery : Journal of the British Society for Surgery of the Hand·Y D GuL Chen
Nov 1, 1991·The Journal of Physiology·J G ColebatchA Guz
Apr 15, 1993·Proceedings of the National Academy of Sciences of the United States of America·A MogilnerR R Llinás
Apr 1, 1993·Journal of Neurology, Neurosurgery, and Psychiatry·G D Schott
Apr 2, 1998·Journal of Reconstructive Microsurgery·Y D GuL Chen
Dec 22, 1999·The Journal of Hand Surgery : Journal of the British Society for Surgery of the Hand·S WaikakulV Vanadurongwan
Jun 9, 2000·Annual Review of Neuroscience·J N Sanes, J P Donoghue
May 4, 2006·Microsurgery·Jean-Yves BeaulieuChristophe Oberlin
Jan 9, 2007·NeuroImage·Daisuke TsuzukiIppeita Dan
Oct 22, 2008·Hand Clinics·Julia K TerzisEpaminondas Kostopoulos
Sep 3, 2011·Experimental Neurology·Yukio Nishimura, Tadashi Isa
Dec 17, 2011·The Journal of Hand Surgery·David Chwei-Chin Chuang, Catherine Hernon
Jan 20, 2012·The Journal of Bone and Joint Surgery. American Volume·Douglas M SammerAlexander Y Shin
Mar 31, 2012·Human Brain Mapping·Pei-Yi LinSang-I Lin
May 24, 2015·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Ken MatsudaKo Hosokawa

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