Motor cortical activity related to movement kinematics exhibits local spatial organization

Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
Eran StarkMoshe Abeles

Abstract

While it is generally accepted that multiple neurons cooperate to generate movement, the precise mechanisms are largely unknown. One way to generate a robust local control signal is for nearby neurons to share similar properties. To study this possibility, we recorded neural activity from the macaque motor cortex during two drawing tasks: free scribbling, and tracing given paths. We analyzed neural activity in relation to three kinematic parameters - position, velocity, and acceleration - while explicitly considering temporal correlations between them. Single-unit (SU) activity was typically related to one parameter, most often velocity, and tended to precede movement. Different SUs encoded different parameters, but nearby units tended to prefer the same parameter. Moreover, while SUs covered a wide range of positions, velocity directions, and acceleration directions, SUs recorded by the same electrode tended to prefer similar values of the same parameter. Nevertheless, some nearby units exhibited marked differences. Multi-unit activity (MUA), estimating the spiking activity of many neurons around the recording electrode, also tended to be related to one parameter and precede movement. However, overall correlations between MUA ...Continue Reading

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Aug 3, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Eran Stark, Moshe Abeles
Aug 24, 2007·The European Journal of Neuroscience·Eran StarkMoshe Abeles

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Citations

Jan 12, 2013·Experimental Brain Research·Shellie A BoudreauLars Arendt-Nielsen
Oct 19, 2010·Journal of Computational Neuroscience·Alexander HanuschkinMarkus Diesmann
Apr 6, 2011·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Jennifer A Foley, Sergio Della Sala
Apr 29, 2009·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Nicholas G Hatsopoulos
Mar 29, 2014·Advanced Materials·Pouria FattahiMohammad Reza Abidian
Feb 9, 2010·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Jennifer A Foley, Sergio Della Sala
Jan 10, 2009·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Luigi TrojanoTamar Flash
Jan 19, 2010·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Jennifer A Foley, Sergio Della Sala
Mar 6, 2012·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Allan MartinAndres M Lozano

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