Motor deficits cannot explain impaired cognitive associative learning in cerebellar patients

Neuropsychologia
Dagmar TimmannH C Diener

Abstract

There is a strong evidence that the cerebellum is involved in associative motor learning. The exact role of the cerebellum in motor learning, and whether it is involved in cognitive learning processes too, are still controversially discussed topics. A common problem of assessing cognitive capabilities of cerebellar patients is the existence of additional motor demands in all cognitive tests. Even if the patients are able to cope well with the motor requirements of the task, their performance could still involve compensating strategies which cost them more attentional resources than the normal controls. To investigate such interaction effects of cognitive and motor demands in cerebellar patients, we conducted a cognitive associative learning paradigm and varied systematically the motor demands and the cognitive requirements of the task. Nine patients with isolated cerebellar disease and nine matched healthy controls had to learn the association between pairs of color squares, presented centrally on a computer monitor together with a left or right answer button. In the simple motor condition, the answer button had to be pressed once and in the difficult condition three times. We measured the decision times and evaluated the corre...Continue Reading

References

Sep 1, 1990·Brain and Cognition·C W Wallesch, A Horn
Jun 1, 1989·Brain : a Journal of Neurology·A W InhoffR Ivry
Oct 1, 1988·Brain : a Journal of Neurology·N MaiJ Dichgans
Aug 1, 1986·Behavioral Neuroscience·H C LeinerR S Dow
Mar 1, 1995·Behavioural Brain Research·I Daum, H Ackermann
Jan 1, 1994·Experimental Brain Research·F Müller, J Dichgans
Oct 1, 1993·Annals of Neurology·A Pascual-LeoneM Hallett
Aug 1, 1993·Brain : a Journal of Neurology·H TopkaM Hallett
Jan 1, 1996·Neuron·J A Fiez
May 24, 1996·Science·J L RaymondM D Mauk
Dec 1, 1996·Behavioral Neuroscience·J TuckerR E Passingham
Nov 20, 1997·Brain : a Journal of Neurology·M MolinariL Petrosini
Jun 17, 1998·Experimental Brain Research·M Gómez-BeldarrainA Pascual-Leone
Mar 2, 1999·Brain : a Journal of Neurology·J DrepperH C Diener
Jun 1, 1997·The Behavioral and Brain Sciences·V BraitenbergF Sultan
Apr 29, 1999·Brain : a Journal of Neurology·K BürkT Klockgether
Mar 1, 1997·Learning & Memory·R LlinásJ P Welsh
Sep 4, 1999·Experimental Brain Research·D J Serrien, M Wiesendanger
Feb 16, 2000·Journal of Neurology, Neurosurgery, and Psychiatry·M MaschkeD Timmann
Feb 26, 2000·Neuropsychologia·D J Serrien, M Wiesendanger
Mar 17, 2000·Brain Research. Brain Research Reviews·F A Middleton, P L Strick
May 10, 2000·Behavioural Brain Research·R F ThompsonP Shinkman
May 12, 2000·Neuroscience Letters·M MaschkeD Timmann
Jul 19, 2000·Current Biology : CB·M D MaukT Ohyama
Aug 10, 2000·Experimental Brain Research·R E PassinghamM F Rushworth
Sep 1, 1998·Trends in Cognitive Sciences·C H Yeo, G Hesslow
Sep 1, 1998·Trends in Cognitive Sciences·W T Thach
Sep 1, 1998·Trends in Cognitive Sciences·J E Desmond, J A Fiez
Oct 1, 1994·Journal of Cognitive Neuroscience·N A Akshoomoff, E Courchesne

❮ Previous
Next ❯

Citations

Jul 4, 2012·The Cerebellum·Giorgos P Argyropoulos, Neil G Muggleton
Oct 26, 2005·Brain and Language·Timothy JustusRichard B Ivry
Sep 4, 2008·Journal of the International Neuropsychological Society : JINS·Shawn W Ell, Richard B Ivry
Jun 1, 2004·Learning & Memory·Markus FringsDagmar Timmann
Feb 13, 2003·Annals of the New York Academy of Sciences·Hanneke I Van Mier, Steve E Petersen
Aug 30, 2008·Journal of Cognitive Neuroscience·Rebecca M C Spencer, Richard B Ivry
Aug 26, 2011·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Sanja Budisavljevic, Narender Ramnani
Apr 24, 2010·Psychiatry Research·Krista Lisdahl MedinaSusan F Tapert
Jun 18, 2003·Human Brain Mapping·Maren CarbonDavid Eidelberg
Mar 1, 2012·Wiley Interdisciplinary Reviews. Cognitive Science·Christian BellebaumBoris Suchan
Aug 30, 2005·Neuropsychologia·Catherine J StoodleyJohn F Stein
Jan 22, 2013·Brain and Language·Hyo Jung De SmetPeter Mariën
Jul 6, 2014·Frontiers in Systems Neuroscience·Laurentiu S PopaTimothy J Ebner
Oct 19, 2007·Developmental Neurorehabilitation·Delphine CalluGeorges Dellatolas
Apr 30, 2004·Journal of Neurophysiology·B SchochD Timmann
Dec 29, 2020·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Daniele GattiGiuliana Mazzoni
Dec 19, 2020·Nature Communications·Christophe J DuboisSiqiong June Liu
Mar 17, 2006·Behavioral and Brain Functions : BBF·Eliana A Quintero-GallegoFco Javier Pérez-Santamaría

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
Christian Bellebaum, Irene Daum
Neuropsychology Review
Janna M Glozman, David E Tupper
© 2022 Meta ULC. All rights reserved