Motor facilitation during action observation: The role of M1 and PMv in grasp predictions

Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
Toon T de BeukelaarNicole Wenderoth

Abstract

Recent theories propose that movement observation is not a "passive mirror" of ongoing actions but might induce anticipatory activity when predictable movements are observed, e.g., because the action goal is known. Here we investigate this mechanism in a series of 3 experiments, by applying transcranial magnetic stimulation (TMS) to primary motor cortex (M1) while subjects observed either whole hand or precision grasping performed by an actor. We show that corticomotor excitability changes in a grip-specific manner but only once the grip can be decoded based on the observed kinematic cues (Exp. 1). By contrast, presenting informative contextual precues evokes anticipatory modulations in M1 already during the reach phase, i.e., well before the grip type could be observed, a finding in line with a predictive coding account (Exp. 2). Finally, we used paired-pulse (PP) TMS to show that ventral premotor cortex (PMv) facilitates grip-specific representations in M1 but only while grip formation is observed. These findings suggest that PMv and M1 interact temporarily and mainly when motor aspects of hand-object interactions are extracted from visual information. By contrast, no sustained input from PMv to M1 seems to be required to mai...Continue Reading

References

Jan 1, 1992·Experimental Brain Research·G di PellegrinoG Rizzolatti
Jul 1, 1987·The Journal of Physiology·C W HessN M Murray
Jul 1, 1995·Trends in Neurosciences·M JeannerodH Sakata
Jun 1, 1995·Journal of Neurophysiology·L FadigaG Rizzolatti
Mar 1, 1996·Brain Research. Cognitive Brain Research·G RizzolattiL Fogassi
Apr 1, 1997·Experimental Brain Research·H DevanneC Capaday
Oct 27, 1997·Journal of Neurophysiology·A MurataG Rizzolatti
Dec 9, 1998·Proceedings of the National Academy of Sciences of the United States of America·R HariG Rizzolatti
Oct 6, 1999·The European Journal of Neuroscience·F BinkofskiH Freund
Jun 5, 2001·Neuroreport·M GangitanoA Pascual-Leone
Jun 25, 2002·Biological Psychiatry·Alvaro Pascual-LeoneDonald C Goff
Jun 26, 2004·Annual Review of Neuroscience·Giacomo Rizzolatti, Laila Craighero
Nov 24, 2004·Nature Neuroscience·James M KilnerAngela Sirigu
Apr 16, 2005·Current Opinion in Neurobiology·Luciano FadigaEtienne Olivier
Oct 28, 2005·Journal of Neurophysiology·Vassilis RaosVittorio Gallese
Jan 27, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Antonia F de C Hamilton, Scott T Grafton
Feb 24, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Marco DavareEtienne Olivier
Jul 28, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Cosimo UrgesiSalvatore M Aglioti
Apr 13, 2007·Cognitive Processing·James M KilnerChris D Frith
Jun 20, 2007·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Barbara MarconiCarlo Caltagirone
Dec 18, 2007·Current Biology : CB·Alessio AvenantiSalvatore Maria Aglioti
Apr 9, 2008·Brain Research Bulletin·Laila CraigheroLuciano Fadiga
Dec 23, 2008·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Kaat AlaertsNicole Wenderoth
Apr 7, 2009·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Marco DavareRoger N Lemon
Aug 14, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·James M KilnerChris D Frith
Apr 10, 2010·The European Journal of Neuroscience·Kaat AlaertsLuciano Fadiga
May 21, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Morrison N LohMarco Davare
Nov 10, 2010·Frontiers in Human Neuroscience·Philippe A Chouinard, Tomáš Paus
Nov 12, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Marie-Christine FluetHansjörg Scherberger
Jul 26, 2011·Neuroscience and Biobehavioral Reviews·Pascal MolenberghsJason B Mattingley
Nov 11, 2011·PloS One·Cinthia M Saucedo MarquezNicole Wenderoth
Jan 1, 2011·Brain Connectivity·Karl J Friston

❮ Previous
Next ❯

Citations

Nov 1, 2017·Physiological Reports·Louis-Solal GiboinVéronique Marchand-Pauvert
Feb 28, 2019·Journal of Neurophysiology·Andreea Loredana CretuNicole Wenderoth
Apr 9, 2020·Experimental Brain Research·Andreea Loredana CretuNicole Wenderoth
Jul 23, 2018·Experimental Brain Research·Heather R McGregorPaul L Gribble
Sep 25, 2017·Somatosensory & Motor Research·Takashi HasegawaToshio Higashi
Mar 8, 2021·Behavioural Brain Research·Ivo Lopes AzevedoAnaelli A Nogueira-Campos
Jul 24, 2021·Cerebral Cortex·Sonia BettiCosimo Urgesi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.