Motor Impairment and Developmental Psychotic Risk: Connecting the Dots and Narrowing the Pathophysiological Gap

Schizophrenia Bulletin
Michele PolettiAndrea Raballo

Abstract

The motor system in its manifold articulations is receiving increasing clinical and research attention. This is because motor impairments constitute a central, expressive component of the mental state examination and a key transdiagnostic feature indexing disease severity. Furthermore, within the schizophrenia spectrum, the integration of neurophysiological, developmental, and phenomenological perspectives suggests that motor impairment is not simply a generic, extrinsic proxy of an altered neurodevelopment, but might be more intimately related to psychotic risk. Therefore, an increased understanding, conceptualization, and knowledge of such motor system and its anomalies could empower contemporary risk prediction and diagnostic procedures.

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Citations

Aug 29, 2020·Current Opinion in Psychiatry·Andrea Raballo, Michele Poletti
Jul 22, 2020·Harvard Review of Psychiatry·Michele Poletti, Andrea Raballo
Dec 22, 2020·Frontiers in Psychiatry·Maija LindgrenJaana Suvisaari
Jan 15, 2021·Psychological Medicine·Ania M FiksinskiAnne S Bassett
Feb 14, 2021·NPJ Schizophrenia·Michele Poletti, Andrea Raballo
May 25, 2021·CNS Spectrums·Michele PolettiAndrea Raballo
Jun 16, 2021·Progress in Neuro-psychopharmacology & Biological Psychiatry·Francesco Luciano DonatiFabio Ferrarelli

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