Motor Preparation Disrupts Proactive Control in the Stop Signal Task

Frontiers in Human Neuroscience
Wuyi WangChiang-shan R Li

Abstract

In a study of the stop signal task (SST) we employed Bayesian modeling to compute the estimated likelihood of stop signal or P(Stop) trial by trial and identified regional processes of conflict anticipation and response slowing. A higher P(Stop) is associated with prolonged go trial reaction time (goRT)-a form of sequential effect-and reflects proactive control of motor response. However, some individuals do not demonstrate a sequential effect despite similar go and stop success (SS) rates. We posited that motor preparation may disrupt proactive control more in certain individuals than others. Specifically, the time interval between trial and go signal onset-the fore-period (FP)-varies across trials and a longer FP is associated with a higher level of motor preparation and shorter goRT. Greater motor preparatory activities may disrupt proactive control. To test this hypothesis, we compared brain activations and Granger causal connectivities of 81 adults who demonstrated a sequential effect (SEQ) and 35 who did not (nSEQ). SEQ and nSEQ did not differ in regional activations to conflict anticipation, motor preparation, goRT slowing or goRT speeding. In contrast, SEQ and nSEQ demonstrated different patterns of Granger causal conne...Continue Reading

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Citations

Dec 18, 2018·The European Journal of Neuroscience·Pascal PasMatthijs Vink
Sep 25, 2018·Drug and Alcohol Dependence·Wuyi WangChiang-Shan R Li

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Software Mentioned

SPM
Statistical Parametric Mapping ( SPM12
nSEQ

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