Motor Skills Are Strengthened through Reconsolidation

Current Biology : CB
Nicholas F WymbsPablo A Celnik

Abstract

Newly acquired motor skills become stabilized through consolidation [1]. However, we know from daily life that consolidated skills are modified over multiple bouts of practice and in response to newfound challenges [2]. Recent evidence has shown that memories can be modified through reconsolidation, in which previously consolidated memories can re-enter a temporary state of instability through retrieval, and in order to persist, undergo re-stabilization [3-8]. Although observed in other memory domains [5, 6], it is unknown whether reconsolidation leads to strengthened motor skills over multiple episodes of practice. Using a novel intervention after the retrieval of a consolidated skill, we found that skill can be modified and enhanced through exposure to increased sensorimotor variability. This improvement was greatest in those participants who could rapidly adjust their sensorimotor output in response to the relatively large fluctuations presented during the intervention. Importantly, strengthening required the reactivation of the consolidated skill and time for changes to reconsolidate. These results provide a key demonstration that consolidated motor skills continue to change as needed through the remapping of motor command ...Continue Reading

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Citations

Nov 1, 2016·Neurorehabilitation and Neural Repair·Robert M HardwickPablo A Celnik
Apr 4, 2017·Acta Ophthalmologica·Ann Sofia Skou ThomsenLars Konge
Jul 10, 2017·Vision Research·Chéla R Willey, Zili Liu
Oct 28, 2016·Journal of Neurophysiology·Rodrigo S MaedaDaniel S Marigold
Mar 2, 2018·PloS One·Baptiste CaramiauxCaroline Palmer
May 3, 2019·Journal of Neurophysiology·Vikram A RajanPablo A Celnik
Nov 18, 2016·Royal Society Open Science·Juliet McClymontKarl T Bates
Jun 12, 2019·Journal of Vision·Shira Klorfeld-Auslender, Nitzan Censor
Aug 21, 2019·Frontiers in Robotics and AI·Ekin BasalpPeter Wolf
Jun 6, 2021·Proceedings of the National Academy of Sciences of the United States of America·Jasmine HerszageNitzan Censor
Sep 16, 2021·Journal of Speech, Language, and Hearing Research : JSLHR·Tanya MatthewsSusan Rvachew

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