Mouse endogenous superantigens: Ms and Mls-like determinants encoded by mouse retroviruses

Current Protocols in Immunology
R J Hodes, R Abe

Abstract

Commonly used inbred mouse strains express different combinations of integrated mouse mammary tumor proviruses (MMTV). This appendix summarizes the proviruses that have been detected. The reported functional properties of those MMTV proviral products which have been identified as superantigens are also summarized, including the ability to elicit primary or secondary T cell responses and to induce Vb-specific clonal deletion during T cell differentiation. In addition, the amino acid sequences of putative ORF gene products of different MMTV are compared.

Citations

Mar 27, 2019·The Journal of Clinical Investigation·Lucas P WachsmuthChristopher G Kanakry
Oct 6, 2019·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Lucas P WachsmuthChristopher G Kanakry
Dec 4, 2009·Molecular Immunology·Patrick KilgannonBhagirath Singh

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