PMID: 3768889Aug 15, 1986Paper

Mouse liver gangliosides

Carbohydrate Research
M SuzukiT Yamakawa

Abstract

The major gangliosides from mouse liver were purified and characterized by t.l.c., g.l.c., sialidase treatment, and a methylation study. GM3(NeuAc), GM3(NeuGc), GM2(NeuGc), GM1(NeuGc), and GDla(NeuGc, NeuGc) were identified. The structural identification of three of the gangliosides, GM2(NeuGc), GM1(NeuGc), and GDla(NeuGc, NeuGc), was supported by the results of 1H-n.m.r. analysis, and the structures of GM3(NeuGc), GM2(NeuGc), and GM1(NeuGc) were further confirmed by negative-ion fast-atom bombardment mass spectrometry. Ganglioside mapping showed that there was polymorphic variation of gangliosides in the liver of inbred strains of mice and that the major gangliosides were GM3(NeuGc) in WHT/Ht, GM2(NeuGc) in BALB/c and C3H/He, and GM2(NeuGc), GM1(NeuGc), and GDla(NeuGc, NeuGc) in ICR mice. Gangliosides containing N-acetylneuraminic acid, except for GM3(NeuAc), were not detected as major gangliosides in the strains of mice we analyzed.

References

Jan 1, 1984·Advances in Experimental Medicine and Biology·G TettamantiA Fiorilli
Jan 1, 1984·Advances in Experimental Medicine and Biology·A SuzukiT Yamakawa
Oct 1, 1984·Journal of Biochemistry·K NakamuraT Yamakawa
Dec 1, 1983·Journal of Biochemistry·Y HashimotoK Moriwaki
Jan 1, 1984·Journal of Biochemistry·Y HashimotoK Moriwaki
Mar 1, 1983·The Biochemical Journal·R GhidoniG Tettamanti
Mar 1, 1983·Journal of Biochemistry·Y HashimotoT Yamakawa
Mar 1, 1982·Journal of Biochemistry·Y HashimotoT Yamakawa
Sep 1, 1963·Journal of Neurochemistry·L SVENNERHOLM

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Citations

Oct 1, 1988·Biochemical Genetics·D Sokoloff, P Hechtman
Jun 1, 1996·Lipids·R M HannV A Eterovic
Dec 15, 1986·Chemistry and Physics of Lipids·T YamakawaY Hashimoto
Nov 1, 1990·Developmental Biology·D E LorkeH Rösner
Aug 28, 2001·Biochimie·A Varki
May 18, 1999·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·H HildebrandtH Rahmann
Jul 4, 2001·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·M SaitoK Sugiyama
Oct 12, 2014·Glycobiology·Masakazu NagafukuJin-Ichi Inokuchi
Feb 15, 1988·International Journal of Cancer. Journal International Du Cancer·I KawashimaT Tai
Oct 10, 1998·Journal of Virology·M D RolsmaM S Kuhlenschmidt

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