Mouse Resource Browser--a database of mouse databases.

Database : the Journal of Biological Databases and Curation
Michael ZouberakisVassilis Aidinis

Abstract

The laboratory mouse has become the organism of choice for discovering gene function and unravelling pathogenetic mechanisms of human diseases through the application of various functional genomic approaches. The resulting deluge of data has led to the deployment of numerous online resources and the concomitant need for formalized experimental descriptions, data standardization, database interoperability and integration, a need that has yet to be met. We present here the Mouse Resource Browser (MRB), a database of mouse databases that indexes 217 publicly available mouse resources under 22 categories and uses a standardised database description framework (the CASIMIR DDF) to provide information on their controlled vocabularies (ontologies and minimum information standards), and technical information on programmatic access and data availability. Focusing on interoperability and integration, MRB offers automatic generation of downloadable and re-distributable SOAP application-programming interfaces for resources that provide direct database access. MRB aims to provide useful information to both bench scientists, who can easily navigate and find all mouse related resources in one place, and bioinformaticians, who will be provided ...Continue Reading

References

Jul 18, 2006·Nucleic Acids Research·Duncan HullTom Oinn
Jan 16, 2007·Cell·Francis S CollinsWolfgang Wurst
Feb 14, 2007·Nature Reviews. Genetics·Morris A Swertz, Ritsert C Jansen
Sep 1, 2007·Nature Cell Biology·Nadia Rosenthal, Steve Brown
Dec 30, 2008·Briefings in Bioinformatics·Damian SmedleyPaul Schofield

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Citations

Jul 16, 2010·Database : the Journal of Biological Databases and Curation·Damian SmedleyJohn M Hancock
Mar 17, 2012·Human Mutation·Paul N SchofieldGeorgios V Gkoutos
Oct 21, 2011·Disability and Rehabilitation·Amy M DennettKevin Mulrain
Nov 26, 2010·The American Journal of Bioethics : AJOB·Richard PayneMyra Christopher
Nov 26, 2010·The American Journal of Bioethics : AJOB·Evan Anderson, Scott Burris
Jun 15, 2012·Journal of Psychopharmacology·Chao DengXu-Feng Huang
Jan 14, 2012·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Amy M SalehColin L W Driscoll
Jan 13, 2018·Physics in Medicine and Biology·Mattia DonzelliStefan Bartzsch
Jan 25, 2018·Physics in Medicine and Biology·Gerard Ariño-EstradaSimon R Cherry
Nov 9, 2018·Australasian Psychiatry : Bulletin of Royal Australian and New Zealand College of Psychiatrists·Lily Xu, Saroja Krishnaswamy

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Methods Mentioned

BETA
targeted mutations

Software Mentioned

Taverna
BioMart
CASIMIR
Glassfish
wsAnalyzer
MOLGENIS
wsGenerator
WebServices
PostgreSQL
MOLGENIS biosoftware

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