Movement disorders in children with congenital Zika virus syndrome.

Brain & Development
Hélio van der LindenAlex Paciorkowski

Abstract

Congenital Zika Virus Syndrome (CZVS) denotes the neurologic and developmental sequelae of congenital infection of the Zika virus. While prior studies have detailed the associated clinical phenotypes, new findings continue to be identified. Abnormal postures and movements have been previously described in children with CZVS, but not in detail. To examine a cohort of infants with CZVS and characterize the spectrum of motor abnormalities, especially movement disorders. Cross-sectional prospective study of 21 infants with confirmed CZVS. Single-center cohort of 32 patients with serologically confirmed CZVS cared for in a referral center in Brazil. 21 children (67% female), evaluated by two child neurologists and one movement disorders specialist, with clinical and laboratory diagnosis of CZVS aged between 16 and 30 months, with a mean age of 16 months at the time of the last examination. Prospective neurologic examination by a team of three neurologists, including one movement disorders specialist. Sixteen (76.2%) children had a longitudinal evaluation with a six-month interval. The same team of experts analyzed recorded videos of all patients to characterize motor abnormalities and movement disorders. Neuroimaging findings were a...Continue Reading

Citations

Aug 19, 2021·Movement Disorders Clinical Practice·Annu AggarwalMohit Bhatt
Sep 4, 2021·Revista da Escola de Enfermagem da U S P·Emanuele Mariano de Souza SantosAndréa Monteiro Correia Medeiros

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