Movement disorders in systemic autoimmune diseases: Clinical spectrum, ancillary investigations, pathophysiological considerations.

Parkinsonism & Related Disorders
Elisa MenozziBettina Balint

Abstract

With the advances in neuroimmunology especially due to the discovery of new neuronal antibodies, the recognition of treatable antibody-related movement disorders has recently received much attention. In contrast, the identification and characterisation of movement disorders associated with systemic autoimmune diseases remains a substantially unexplored area. Beyond the classic few associations such as chorea and antiphospholipid syndrome, or ataxia and coeliac disease, movement disorders have been reported in association with several systemic autoimmune diseases, however a clear image of clinical phenotypes, investigations, and treatment outcomes in these conditions has never been drawn. In this review, we analyse data from approximately 300 cases and summarise the epidemiological, clinical and diagnostic features of movement disorders associated with systemic autoimmune diseases, and the available knowledge about treatment and outcomes. We highlight that movement disorders in systemic autoimmune conditions are frequently the only or among a few presenting manifestations and are mostly treatable disorders responding to immunotherapy or dietary modifications. We point out the pertinent combination of clinical features and invest...Continue Reading

References

Oct 1, 1992·Acta Neurologica Scandinavica·M E LancmanJ Norscini
Nov 1, 1995·The Journal of Allergy and Clinical Immunology·R C KunasP M Villiger
May 1, 1995·Journal of Neurology·F G Akman-DemirO Aral
Nov 1, 1994·Clinical Neurology and Neurosurgery·H NishimuraM Sugita
May 1, 1994·Journal of the Neurological Sciences·K KuroeH Takemori
Aug 7, 1993·Lancet·T ShimomuraK Takahashi
Jul 1, 1993·Movement Disorders : Official Journal of the Movement Disorder Society·L AngeliniG Pellegrini
Jun 1, 1993·Clinical Neurology and Neurosurgery·L H VisserJ P van de Merwe
Oct 1, 1995·Lupus·H F al-Arfaj, H O Naddaf
May 1, 1996·Clinical Neurology and Neurosurgery·M U MantoJ G Hildebrand
Jan 1, 1997·Movement Disorders : Official Journal of the Movement Disorder Society·A CréangeJ D Degos
May 1, 1997·Journal of Neurophysiology·E J SchicatanoC Evinger
Oct 27, 1997·Neurology·P F ChinneryD M Turnbull
Feb 6, 1998·Movement Disorders : Official Journal of the Movement Disorder Society·J Sundén-CullbergS M Aquilonius
Apr 9, 1998·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·D BogdanovaD Georgiev
Jul 3, 1998·Pediatric Neurology·E ShaharE Lahat
Jan 26, 1999·Movement Disorders : Official Journal of the Movement Disorder Society·M T PellecchiaP Barone
Mar 26, 1999·Movement Disorders : Official Journal of the Movement Disorder Society·R H WalkerC W Olanow
Mar 26, 1999·Movement Disorders : Official Journal of the Movement Disorder Society·J S van den BergW J Oyen
Apr 22, 1999·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·S M LimR J Abbott
May 29, 1999·Movement Disorders : Official Journal of the Movement Disorder Society·H R Morris, A J Lees
Sep 24, 1999·Movement Disorders : Official Journal of the Movement Disorder Society·B Jabbari, A Salardini
Mar 16, 2000·Clinical Neurology and Neurosurgery·M YaginumaM Sakamoto
Apr 4, 2000·Neurology·M A TijssenP Brown
Aug 6, 2000·Movement Disorders : Official Journal of the Movement Disorder Society·V S FungI T Lorentz
Mar 15, 2001·Parkinsonism & Related Disorders·I Milanov, D Bogdanova
Sep 29, 2001·Journal of Child Neurology·J A GottfriedR S Finkel
Nov 24, 2001·Journal of the Neurological Sciences·E K TanA P Auchus
Mar 27, 2002·European Neurology·Tae-Ho GuakJoong-Seok Kim
Apr 16, 2002·Arthritis and Rheumatism·Ricard CerveraUNKNOWN Euro-Phospholipid Project Group
May 9, 2002·Journal of the Neurological Sciences·Kiyoshi OwadaKuniaki Tsuchiya
Jul 12, 2002·Movement Disorders : Official Journal of the Movement Disorder Society·Giorgio FabianiLineu César Werneck
Dec 5, 2002·Movement Disorders : Official Journal of the Movement Disorder Society·José Manuel García-Moreno, José Chacón
Jan 24, 2004·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Toru Watanabe, Hiroo Onda
Apr 13, 2004·Movement Disorders : Official Journal of the Movement Disorder Society·Anthony C PereiraKailash P Bhatia
Jun 24, 2004·Neurology·S WongD J Dlugos
Aug 5, 2004·Clinical Rheumatology·Rika KuriwakaTakao Mitsui
Sep 25, 2004·Movement Disorders : Official Journal of the Movement Disorder Society·Marc Engelen, Marina A J Tijssen

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antiphospholipid Syndrome

Antiphospholipid syndrome or antiphospholipid antibody syndrome (APS or APLS), is an autoimmune, hypercoagulable state caused by the presence of antibodies directed against phospholipids.

Ataxias (MDS)

Ataxia is a neurological condition characterized by lack of voluntary coordination of muscle movements including loss of coordination, balance, and speech. Discover the latest research on ataxia here.

Ataxia

Ataxia is a neurological condition characterized by lack of voluntary coordination of muscle movements including loss of coordination, balance, and speech. Discover the latest research on ataxia here.

Ataxias

Ataxia is a neurological condition characterized by lack of voluntary coordination of muscle movements including loss of coordination, balance, and speech. Discover the latest research on different types of ataxias here.

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.

Related Papers

Movement Disorders : Official Journal of the Movement Disorder Society
José Fidel Baizabal-Carvallo, Joseph Jankovic
Continuum : Lifelong Learning in Neurology
Toni S Pearson, Roser Pons
Seminars in Neurology
Conor Fearon, Orna O'Toole
European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society
Shekeeb S Mohammad, Russell C Dale
© 2021 Meta ULC. All rights reserved