May 20, 2017

Movement Does Not Promote Recovery of Motor Output Following Acute Experimental Muscle Pain

Pain Medicine : the Official Journal of the American Academy of Pain Medicine
Siobhan M SchabrunThomas Graven-Nielsen


To examine the effect of motor activity on the magnitude and duration of altered corticomotor output following experimental muscle pain. Experimental, pre-post test. University laboratory. Twenty healthy individuals. Participants were randomly allocated to a Rest or Movement group. The Rest group sat quietly without moving for the duration of the experiment. The Movement group repeated a unimanual pattern of five sequential keystrokes as quickly and as accurately as possible immediately following the resolution of pain. Pain was induced into the right extensor carpi radialis brevis muscle by a bolus injection of 0.5 mL hypertonic saline. Corticomotor output was assessed as motor evoked potentials in response to transcranial magnetic stimulation before, immediately after, and at 10, 20, and 30 minutes following pain resolution. Pain intensity was recorded every 30 seconds using an 11-point numerical rating scale. There was no difference in peak pain intensity (P < 0.09) or duration (P < 0.2) between groups. Corticomotor output was reduced in both groups (P < 0.002) at 10 minutes (P < 0.002), 20 minutes (P < 0.02), and 30 minutes (P < 0.037) following the resolution of pain relative to baseline. There was no difference between gr...Continue Reading

  • References22
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  • References22
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Mentioned in this Paper

Molecular Motor Activity
Neural Inhibition
Skeletal Muscle Tender
Recurrent Malignant Neoplasm
Motor Neuropathy Peripheral With Dysautonomia
Recurrence (Disease Attribute)

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