Moyamoya disease: a comparison of long term outcome of conservative and surgical treatment in India

Journal of the Neurological Sciences
Soumya SundaramSankara Sarma

Abstract

Revascularization surgery (RS) is the therapy of choice in moyamoya disease (MMD). Due to rarity of disease and ethical concerns, randomized controlled trials about the treatment options are lacking. Very little information is available on the long-term outcome of conservatively treated moyamoya patients. We compared the long-term outcome of moyamoya patients treated conservatively to those who underwent RS. Our study population included all patients with moyamoya disease/syndrome from 2002 to 2012. The demographic, clinical characteristic and imaging details were reviewed. The outcome was obtained prospectively. Of the 36 patients, 26 (72.2%) had MMD and 10 (27.8%) had moyamoya syndrome. The median age at onset of symptoms was 17.5 years (range, 10 months-55 years). Fifteen patients belonged to pediatric group and 21 were adults. All the pediatric patients had ischemic events at onset and 10 (47.6%) of the adults presented with hemorrhage. Twenty (55.6%) patients received conservative treatment and 16 (44.4%) underwent revascularization procedures. The median duration of follow-up was 28 months (range, 3-90 months). Three (18%) of the surgically treated patients had recurrent ischemic events on follow-up, but none of the conse...Continue Reading

References

Jul 11, 1998·Stroke; a Journal of Cerebral Circulation·D ChiuJ C Grotta
Jun 1, 2000·Journal of Child Neurology·K Ikezaki
Sep 24, 2005·Stroke; a Journal of Cerebral Circulation·Satoshi KurodaYoshinobu Iwasaki
Sep 28, 2005·Neurology·Ken UchinoDavid L Tirschwell
Apr 29, 2006·Stroke; a Journal of Cerebral Circulation·Christopher L HallemeierColin P Derdeyn
May 11, 2006·Cerebrovascular Diseases·Michael E KellyGary K Steinberg
Dec 1, 2007·Stroke; a Journal of Cerebral Circulation·Shinichi KuriyamaTakashi Yoshimoto
Sep 13, 2008·Stroke; a Journal of Cerebral Circulation·Markus KraemerPeter Berlit
Oct 25, 2011·Stroke; a Journal of Cerebral Circulation·Lian DuanJie Feng

❮ Previous
Next ❯

Citations

Apr 27, 2016·Journal of Neurosciences in Rural Practice·Satyakam Mohapatra, Alok Jyoti Sahoo
Nov 12, 2016·Journal of Neurosurgery·Dong-Kyu JangYoung-Min Han
Mar 6, 2019·Journal of Neurosurgery. Pediatrics·Coleman P RiordanR Michael Scott

❮ Previous
Next ❯

Related Concepts

Related Feeds

Brain Ischemia

Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. Discover the latest research on brain ischemia here.

Related Papers

European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies
Markus KraemerN Khan
European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies
S-H SuY-F Wu
© 2022 Meta ULC. All rights reserved