Moyamoya disease associated with hemophilia A. Case report

Pediatric Neurosurgery
Masahide MatsudaTadao Nose

Abstract

A 10-year-old boy who had been diagnosed as having hemophilia A presented with episodes of transient ischemic attack. Cerebral angiography showed occlusions of the bilateral anterior cerebral arteries and the right middle cerebral artery with the development of an abnormal vascular network. The patient was diagnosed as having moyamoya disease associated with hemophilia A and subsequently underwent multiple burr hole surgery for revascularization under sufficient factor VIII supplementation. He remained asymptomatic after surgery, and follow-up cerebral angiography 5 months after the operation demonstrated significant neovascularization through the burr holes. Multiple burr hole surgery is proposed as a method of choice for the treatment of moyamoya disease associated with a bleeding tendency.

Citations

Jan 18, 2006·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Aiki MarushimaTadao Nose
Nov 13, 2008·Pediatric Blood & Cancer·Torrey M ParkerRobert J Klaassen
Sep 18, 2016·Indian Journal of Pediatrics·Arushi Gahlot SainiPratibha Singhi

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