Moyamoya disease in a European setting: a Danish population-based study.

European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies
Peter BirkelandP von Weitzel-Mudersbach

Abstract

The incidence of moyamoya disease (MMD) in Europe is not well known. In those affected, the risk of brain hemorrhage is considered low. The present study aimed to investigate the incidence and clinical presentation of MMD in the Danish population. Eligible patients were identified in the Danish National Patient Register from 1994 to 2017. We collected clinical and radiological data from individual patient records from neurological, neurosurgical and paediatric units across Denmark. The diagnosis was validated according to established criteria. We also extracted basic demographic data on the cohort from the Danish Civil Registration System. A total of 52 patients fulfilled the diagnostic criteria for MMD. Most patients were native Danes and only 15% had an East Asian background. The ratio of female to male patients was 1.8, and the incidence had two peaks: one in childhood and another in young middle age. Until 2007, MMD was only diagnosed sporadically. From 2008 onwards, the incidence rate was 0.07 per 100 000 person-years (95% confidence interval 0.05-0.09 per 100 000 person-years). The most common mode of presentation was ischaemic stroke (33%), followed by hemorrhage (23%), headache (17%) and transient ischaemic attack (14%)...Continue Reading

References

Sep 28, 2005·Neurology·Ken UchinoDavid L Tirschwell
Dec 14, 2007·Journal of Neurology, Neurosurgery, and Psychiatry·T BabaS Kuroda
Mar 20, 2009·The New England Journal of Medicine·R Michael Scott, Edward R Smith
Mar 2, 2012·Journal of Neurology, Neurosurgery, and Psychiatry·Rachel KleinloogCatharina J M Klijn
Jul 27, 2012·Brain : a Journal of Neurology·Pinki MunotVijeya Ganesan
Aug 9, 2012·Neurologia Medico-chirurgica·UNKNOWN Research Committee on the Pathology and Treatment of Spontaneous Occlusion of the Circle of Willis, UNKNOWN Health Labour Sciences Research Grant for Research on Measures for Infractable Diseases
Apr 8, 2015·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·G AckerP Vajkoczy
Oct 17, 2015·British Journal of Neurosurgery·Pennylouise HeverChristos Tolias
Nov 26, 2015·Clinical Epidemiology·Morten SchmidtHenrik Toft Sørensen
Sep 15, 2016·International Journal of Stroke : Official Journal of the International Stroke Society·Marika SaarelaTurgut Tatlisumak
Sep 2, 2018·Acta Neurochirurgica. Supplement·Peter Birkeland, Jens Lauritsen

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Acta Medica Okayama
Tomohito HishikawaIsao Date
Experimental and Therapeutic Medicine
Hui ZhangLei Feng
European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies
G AckerPeter Vajkoczy
Cerebrovascular Diseases
Anna BersanoEuropean Moyamoya Disease Initiative
© 2021 Meta ULC. All rights reserved