PMID: 15815251Jun 1, 1989Paper

Moyamoya disease: pathophysiology and anesthetic management

Journal of Neurosurgical Anesthesiology
R A Malley, E A Frost


Moyamoya disease, an ischemic cerebrovascular disease, is characterized by a slowly increasing bilateral occlusion of the internal carotid circulation. Although collateral pathways are formed, therapy is aimed at further increasing blood flow by surgical anastomosis before ischemic events and fixed neurologic defects occur. This disease remains one of the few indications for performance of the operation of superficial temporal artery to middle cerebral artery anastomosis. Anesthetic considerations involve increasing substrate supply and decreasing demand for its use. Two cases of moyamoya disease are described, noteworthy not only because of the rarity of the disease but because of its occurrence in the Hispanic race rather than the traditional appearance in those only of Japanese descent. The anesthetic management is outlined and the literature reviewed.


Oct 14, 2000·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·D L WilliamsR M Gully
Oct 1, 1991·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·J D Martino, L O Werner
Feb 1, 1997·Surgical Neurology·M Fukui
Dec 31, 1997·Clinical Neurology and Neurosurgery·M K Edwards-Brown, J P Quets
Dec 31, 1997·Clinical Neurology and Neurosurgery·Y NumaguchiD K Shibata
Aug 12, 2010·Anesthesiology Research and Practice·Vanitha Sivanaser, Pirjo Manninen
Oct 7, 2010·Journal of Neurosurgical Anesthesiology·Tariq ParraySaif Siddiqui
Dec 6, 2005·Paediatric Anaesthesia·Nigar BaykanM Memet Ozek
Jan 28, 2015·Anesthesia and Analgesia·Jason ChuiLashmi Venkatraghavan
Dec 1, 1993·Postgraduate Medical Journal·R S HoulstonN F Lawton

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