In Asian populations, moyamoya disease has a well-defined phenotype including a bimodal age of presentation with children typically presenting with ischemic phenomena and adults presenting with hemorrhage. Studies have provided evidence that moyamoya disease in the United States may exhibit a different phenotype. To assess overall rates of admission, demographics, procedures, and outcomes of patients admitted or diagnosed with moyamoya disorder in US hospitals. A comprehensive assessment of the Nationwide Inpatient Sample of the Healthcare Cost and Utilization Project (2002-2008) was performed. Patient demographics, comorbidities, procedures, and outcomes were analyzed. There were 2280 admissions for moyamoya disorder with a predicted national estimate of 11 163 admissions (0.57/100 000 persons/y). Over time, there was a significant increase in diagnosis and associated ischemic strokes. Females (72%) were affected more than males (28%). Demographics included white (49%), black (24%), Hispanic (11%), Asian (11%), and other (3.3%). Mean age at presentation was 31.6 ± 18.0. Children were significantly more likely to be diagnosed with ischemic phenomena (16.4%) than hemorrhage (3.3%), as were adults (18.8% vs 11.0%). Status at disc...Continue Reading
Direct and indirect revascularization for moyamoya disease surgical techniques and peri-operative complications
Guidelines for the diagnosis and treatment of spontaneous occlusion of the circle of Willis ('moyamoya' disease). Research Committee on Spontaneous Occlusion of the Circle of Willis (Moyamoya Disease) of the Ministry of Health and Welfare, Japan
Guidelines for prevention of stroke in patients with ischemic stroke or transient ischemic attack: a statement for healthcare professionals from the American Heart Association/American Stroke Association Council on Stroke: co-sponsored by the Council on Cardiovascular Radiology and Intervention: the American Academy of Neurology affirms the value of this guideline
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Prevalence and clinicoepidemiological features of moyamoya disease in Japan: findings from a nationwide epidemiological survey
Hyperbaric oxygen reduces tissue hypoxia and hypoxia-inducible factor-1 alpha expression in focal cerebral ischemia
Long-term outcome of superficial temporal artery-middle cerebral artery bypass for patients with moyamoya disease in the US
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Trends in the management of adult moyamoya disease in the United States: results of a nationwide survey
Resolution of bilateral moyamoya associated collateral vessel aneurysms: Rationale for endovascular versus surgical intervention
Are hyperlipidemia and autoimmune diseases synergistic in Moyamoya disease pathophysiology? Insight from the Midwest
Double-barrel bypass for cerebral ischemia: technique, rationale, and preliminary experience with 10 consecutive cases
Moyamoya disease in a primarily white, midwestern US population: increased prevalence of autoimmune disease
National Analysis of 2454 Pediatric Moyamoya Admissions and the Effect of Hospital Volume on Outcomes
Treatment and diagnosis of cerebral aneurysms in the post-International Subarachnoid Aneurysm Trial (ISAT) era: trends and outcomes
Disease Variant Landscape of a Large Multiethnic Population of Moyamoya Patients by Exome Sequencing
Rare variants of RNF213 and moyamoya/non-moyamoya intracranial artery stenosis/occlusion disease risk: a meta-analysis and systematic review
Intracranial Large Artery Disease of Non-Atherosclerotic Origin: Recent Progress and Clinical Implications
Proposing a validated clinical app predicting hospitalization cost for extracranial-intracranial bypass surgery
Time to peak and full width at half maximum in MR perfusion: valuable indicators for monitoring moyamoya patients after revascularization.
Surgical revascularization for Moyamoya disease in the United States: A cost-effectiveness analysis.
Commentary: Surgical Trapping of a Large Complex Middle Cerebral Artery Aneurysm With Double-Barrel Bypass: 3-Dimensional Operative Video.
Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. Discover the latest research on brain ischemia here.