PMID: 15377875DOI: 10.1023/b:jobb.0000041771.66775.d5Sep 21, 2004Paper
MPTP as a mitochondrial neurotoxic model of Parkinson's disease
Journal of Bioenergetics and Biomembranes
Serge PrzedborskiMiquel Vila
Abstract
1-Methy-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is a potent neurotoxin extensively used to model Parkinson's disease (PD). A cascade of deleterous events, in which mitochondria play a pivotal role, drives MPTP neurotoxicity. How mitochondria are affected by MPTP and how their defect contributes to the demise of dopaminergic neurons in this model of PD are discussed in this review.
Citations
May 18, 2007·Der Nervenarzt·A Storch
Aug 27, 2009·Journal of Neural Transmission·Kurt A Jellinger
Sep 19, 2009·Journal of Neural Transmission·Makoto NaoiMasayo Shamoto-Nagai
Jan 24, 2009·Apoptosis : an International Journal on Programmed Cell Death·Oren A LevyLloyd A Greene
Sep 17, 2008·Journal of Molecular Neuroscience : MN·Margarida Castro-CaldasMaria João Gama
Jul 30, 2011·Journal of Molecular Neuroscience : MN·Xiao-Qing TangBi Hu
Aug 15, 2013·Journal of Molecular Neuroscience : MN·Karamkolly R RekhaRamu Inmozhi Sivakamasundari
Dec 30, 2011·Molecular Neurobiology·Ilse S PienaarDavid Dexter
Apr 3, 2010·Neurotoxicity Research·Xiao-Qing TangYuan-Jian Li
Jan 9, 2013·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·Kang-Woo LeeM Maral Mouradian
Dec 27, 2008·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·Cornelis J Van der Schyf, Werner J Geldenhuys
Oct 1, 2010·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·Melinda E Lull, Michelle L Block
May 12, 2005·Parkinsonism & Related Disorders·Serge Przedborski
Mar 14, 2013·Sleep Medicine Reviews·Marcelo M S Lima
Jun 13, 2013·Trends in Genetics : TIG·G Jane FarrarSophia Millington-Ward
Nov 18, 2008·Proceedings of the National Academy of Sciences of the United States of America·Julio SalazarEtienne C Hirsch
Dec 22, 2012·The Journal of Biological Chemistry·Prachi BajpaiNarayan G Avadhani
May 1, 2007·Antioxidants & Redox Signaling·Jie BaiJunji Yodoi
Mar 11, 2009·Antioxidants & Redox Signaling·Saurabh Sen, Andrew B West
Feb 11, 2009·Antioxidants & Redox Signaling·Lichuan YangM Flint Beal
Aug 18, 2010·Antioxidants & Redox Signaling·Dalton James SurmeierJoshua A Goldberg
May 3, 2011·Antioxidants & Redox Signaling·Bobby ThomasAnatoly Starkov
Aug 6, 2009·Rejuvenation Research·Jennifer Barber-SinghTakao Yagi
Feb 4, 2010·Brain : a Journal of Neurology·Shannon LevesqueMichelle L Block
Jul 26, 2013·Brain : a Journal of Neurology·Celine PerierMiquel Vila
May 13, 2005·Human Molecular Genetics·Chee Yeun ChungOle Isacson
Oct 6, 2011·Toxicological Sciences : an Official Journal of the Society of Toxicology·Manjeet SinghCharles Ramassamy
Jul 5, 2012·Cold Spring Harbor Perspectives in Medicine·D James SurmeierPaul T Schumacker
Jun 10, 2010·Clinical and Experimental Pharmacology & Physiology·Xiao-Qing TangDuan-Fan Liao
Oct 12, 2010·Science Translational Medicine·Bin ZhengUNKNOWN Global PD Gene Expression (GPEX) Consortium
Jul 22, 2011·Journal of Toxicology·Julie CarangeMaria-Grazia Martinoli
Mar 27, 2012·The Journal of Clinical Investigation·Senthil SelvarajBrij B Singh
Jul 28, 2009·Molecular Neurodegeneration·João Paulo L DaherDarren J Moore
May 12, 2009·PloS One·Agnès Petit-PaitelJoëlle Chabry
Jan 12, 2012·PloS One·Peizhong MaoP Hemachandra Reddy
Nov 28, 2012·PloS One·Xinru LiDavid G Standaert
Nov 10, 2013·PloS One·Stefan KurtenbachHermann Lübbert
May 9, 2014·PloS One·Jackalina M Van KampenDenis G Kay
Jan 4, 2006·NeuroRx : the Journal of the American Society for Experimental NeuroTherapeutics·Jordi BovéSerge Przedborski
Jun 21, 2011·Parkinson's Disease·Kyota FujitaMami Noda
Dec 29, 2010·Parkinson's Disease·Jennifer Barber-SinghTakao Yagi
Jan 15, 2011·Parkinson's Disease·Ross B Mounsey, Peter Teismann
Apr 5, 2011·Parkinson's Disease·P C KeaneC M Morris
Mar 25, 2009·Neurogenetics·Ignacio F MataCyrus P Zabetian
Jul 10, 2014·Neurochemical Research·Ai-Hua ChenXiao-Qing Tang
Aug 27, 2014·The Journal of Cell Biology·Ghazaleh AshrafiThomas L Schwarz
Oct 12, 2010·Journal of Neural Transmission·Eduardo L G MoreiraRui D S Prediger
Jun 2, 2011·International Journal of Alzheimer's Disease·Venkatramanujam SrinivasanDaniel P Cardinali
Jul 13, 2011·Neurochemical Research·Xiao-Qing TangBi Hu
Apr 8, 2015·Molecular Medicine Reports·Ping KongYun Zhang
❮ Previous
Next ❯
Related Concepts
Related Feeds
Bacterial Respiration
This feed focuses on cellular respiration in bacteria, known as bacterial respiration. Discover the latest research here.
Related Papers
Nature Protocols
Vernice Jackson-Lewis, Serge Przedborski
Nature Neuroscience
R BetarbetJ Timothy Greenamyre
Progress in Neurobiology
D BlumJ M Verna
Lancet Neurology
A H Schapira
Nature Genetics
Yevgenya KraytsbergKonstantin Khrapko