MR-arterioportography: a new technical approach for detection of liver lesions

World Journal of Gastroenterology : WJG
Janine RennertNiels Zorger


To evaluate the benefit and effectiveness of MR-arterioportography (MR-AP) to achieve the highest sensitivity for detection and evaluation of hepatocellular carcinoma (HCC). Twenty liver cirrhosis patients with suspected HCC were included before transarterial chemoembolization. In all patients double-enhanced Magnetic resonance imaging (MRI) was performed. A bolus of 10 mL Magnevist® was injected through a selectively placed catheter in the superior mesenteric artery and MRI of the liver was performed in arterioportographic phase. Two independent readers evaluated number, size and localization of detected lesions. Diagnostic quality was determined using a 4-point scale. Differences were analyzed for significance using a t-test. Interobserver variability was calculated. In all 20 patients (100%), MR-AP was feasible. Diagnostic quality was, in all cases, between 1 and 2 for both modalities and readers. MR-AP detected significantly more lesions than double-enhanced MRI (102.5 vs. 61, respectively, P < 0.0024). The inter-observer variability was 0.881 for MRI and 0.903 for MR-AP. Our study confirmed that the MR-AP as an additional modality for detection of HCC is beneficial, as significantly more lesions were detected compared to M...Continue Reading


Aug 3, 1999·AJR. American Journal of Roentgenology·T KimH Nakamura
Jan 24, 2003·AJR. American Journal of Roentgenology·Yumi NoguchiHironobu Nakamura
Aug 29, 2006·International Journal of Clinical Oncology·Takashi KoyamaKaori Togashi

Related Concepts

Liver Carcinoma
Liver Dysfunction
Malignant Neoplasm of Liver
Magnetization Transfer Contrast Imaging
Liver Cirrhosis
Magnetic Resonance Imaging
Mesenteric Arteries
Catheter Device

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