MR colonography with fecal tagging: barium vs. barium ferumoxsil

Academic Radiology
Michael P AchiamJacob Rosenberg

Abstract

Both magnetic resonance (MR) and computed tomographic (CT) colonography are useful for colon examination. With sensitivities close to those for conventional colonoscopy (CC) for polyps, colonography has been proposed as an alternative to diagnostic CC. MR colonography (MRC) with fecal tagging may be a method of gaining further patient acceptance and widespread use, but the method has to be optimized. The aim of our study was to evaluate the quality of a new contrast agent mixture and to validate a new method for evaluating the tagging efficiency of contrast agents. Twenty patients referred to CC underwent dark lumen MRC prior to the colonoscopy. Two groups of patients received two different oral contrast agents (barium sulfate and barium sulfate/ferumoxsil) as a laxative-free fecal tagging prior to the MRC. After MRC, the contrast agent was rated qualitatively (with the standard method using contrast-to-wall ratio) and subjectively (using a visual analog scale [VAS]) by three different blinded observers. Evaluated both qualitatively and subjectively, the tagging efficiency of barium sulfate/ferumoxsil was significantly better (P < .05) than barium sulfate alone. The VAS method for evaluating the tagging efficiency of contrast a...Continue Reading

References

Sep 15, 1999·Lancet·D WeishauptJ F Debatin
Dec 13, 2002·Topics in Magnetic Resonance Imaging : TMRI·Thomas C Lauenstein, Jörg F Debatin
Dec 6, 2003·The New England Journal of Medicine·Perry J PickhardtWilliam R Schindler
Apr 15, 2004·JAMA : the Journal of the American Medical Association·Peter B CottonHarold Butler
Oct 5, 2006·Abdominal Imaging·M P AchiamJ Rosenberg

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Citations

May 3, 2008·Abdominal Imaging·Michael Patrick AchiamJacob Rosenberg
May 23, 2016·Japanese Journal of Radiology·Piero Boraschi, Francescamaria Donati
Nov 14, 2018·Chembiochem : a European Journal of Chemical Biology·Xingyue YangYumiao Zhang
Dec 25, 2008·Scandinavian Journal of Gastroenterology·Michael P AchiamJacob Rosenberg

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