MR elastography: Spleen stiffness measurements in healthy volunteers--preliminary experience

AJR. American Journal of Roentgenology
Lorenzo MannelliDavid J Lomas

Abstract

The purpose of this article is to establish the range of normal splenic stiffness in healthy volunteers using MR elastography (MRE) and to investigate any correlation with physiologic parameters and driver position. Sixteen volunteers (mean [+/- SD] age, 37 +/- 9 years) with no history of gastrointestinal, hepatobiliary, or cardiovascular disease were recruited. The MRI protocol included T2-weighted axial and gradient-echo MRE sequences using steady-state 60-Hz excitation. Two MRE acquisitions were performed, one with the driver placed on the right side of the abdomen and the other with the driver placed on the left side. Volunteers' body mass index (BMI), arterial mean blood pressure, age, spleen volume, and liver stiffness were also determined. Two radiologists independently measured the spleen stiffness on the MRE inversion images. The correlations between spleen stiffness and BMI, arterial mean blood pressure, age, spleen volume, and liver stiffness were quantified. Sixteen volunteers underwent MRE. With the driver placed on the right side of the abdomen, the mean splenic stiffness was 3,565 +/- 586 Pa (range, 2,353-4,442 Pa); with the driver on the left side of the abdomen, the mean splenic stiffness was significantly (p <...Continue Reading

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Citations

Nov 22, 2011·Current Urology Reports·Lorenzo MannelliMiriam Moshiri
May 21, 2013·Current Problems in Diagnostic Radiology·Lorenzo MannelliJeffrey H Maki
Feb 12, 2013·Seminars in Ultrasound, CT, and MR·Edmund M GodfreyDavid J Lomas
Jan 26, 2013·Journal of Magnetic Resonance Imaging : JMRI·Xiao-li ChenChun-ping Li
Sep 19, 2012·Journal of Magnetic Resonance Imaging : JMRI·Kevin J GlaserRichard L Ehman
Jul 11, 2012·Journal of Magnetic Resonance Imaging : JMRI·Lorenzo MannelliJeffrey H Maki
Nov 26, 2015·Progress in Nuclear Magnetic Resonance Spectroscopy·Kay M PepinKiaran P McGee
Nov 19, 2013·Journal of Magnetic Resonance Imaging : JMRI·Hiroyuki MorisakaNobuyuki Enomoto
May 7, 2013·Ultrasound in Medicine & Biology·Armen P SarvazyanJames F Greenleaf
Dec 10, 2014·Abdominal Imaging·Sudhakar Kundapur Venkatesh, Richard L Ehman
Oct 5, 2016·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Florian DittmannJing Guo
Aug 25, 2011·AJR. American Journal of Roentgenology·Kemal ArdaKenan Köse
Feb 3, 2016·World Journal of Radiology·Gavin LowDavid J Lomas
Jan 26, 2018·NMR in Biomedicine·Philippe GarteiserBernard E Van Beers
May 29, 2018·NMR in Biomedicine·Christian Guenthner, Sebastian Kozerke
Oct 6, 2018·Topics in Magnetic Resonance Imaging : TMRI·Jin WangSudhakar K Venkatesh
Jan 29, 2019·World Journal of Gastroenterology : WJG·Haesung YoonMi-Jung Lee

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