MR imaging characteristics of protoplasmic astrocytomas.

Neuroradiology
Kevin L TayBrian M Tress

Abstract

Protoplasmic astrocytomas are a poorly recognized and uncommon subtype of astrocytoma. While usually categorized with other low-grade gliomas, there is literature to suggest that protoplasmic astrocytomas have differences in biology compared to other gliomas in this group. This paper presents the MR imaging characteristics of a series of eight protoplasmic astrocytomas. We retrospectively reviewed MR images and histopathology of eight consecutive cases of histologically proven protoplasmic astrocytomas. Patients ranged from 17 to 51 years of age with a 5:3 male to female ratio. The tumors were located in the frontal or temporal lobes and tended to be large, well defined, and had a very high signal on T2 (close to cerebrospinal fluid). Generally, a large proportion of the tumor showed substantial signal suppression on T2 fluid-attenuated inversion recovery (FLAIR). Six of the eight lesions also demonstrated a partial or complete rim of reduced apparent diffusion coefficient (ADC) around the T2 FLAIR suppressing portion. The possibility that a primary cerebral neoplasm represents a protoplasmic astrocytoma should be considered in a patient with a large frontal or temporal tumor that has a very high signal on T2 with a large propo...Continue Reading

References

Mar 1, 1991·Journal of Neurosurgery·H G KrouwerM Prados
Feb 1, 1990·Radiology·B L DeanR G Carey
Mar 1, 1971·Radiology·W Gnekow, D Prolo
Jun 1, 1995·American Journal of Clinical Pathology·R A Prayson, M L Estes
Jul 1, 1993·Brain Pathology·C Daumas-Duport
Feb 25, 1999·Journal of Magnetic Resonance Imaging : JMRI·T SugaharaM Takahashi
Jun 3, 1999·Radiology·E A KnoppI I Kricheff
Jun 1, 2007·Journal of Computer Assisted Tomography·Hemant A ParmarSusan Blaser
Jul 10, 2007·Acta Neuropathologica·David N LouisPaul Kleihues
Jan 6, 2010·Pediatric Blood & Cancer·Sue ManleyBarry Pizer

❮ Previous
Next ❯

Citations

Oct 22, 2016·Journal of Medical Imaging and Radiation Oncology·Paul M SimkinFrank Gaillard
Mar 10, 2018·AJNR. American Journal of Neuroradiology·A LasockiM Gonzales
Jun 24, 2020·Scientific Reports·Shoichi DeguchiNakamasa Hayashi
Jul 29, 2017·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Sohil H PatelRajan Jain
Oct 8, 2021·The British Journal of Radiology·Catarina PintoCristina Ramos

❮ Previous
Next ❯

Related Concepts

Related Feeds

Astrocytes

Astrocytes are glial cells that support the blood-brain barrier, facilitate neurotransmission, provide nutrients to neurons, and help repair damaged nervous tissues. Here is the latest research.

CSF & Lymphatic System

This feed focuses on Cerebral Spinal Fluid (CSF) and the lymphatic system. Discover the latest papers using imaging techniques to track CSF outflow into the lymphatic system in animal models.

Related Papers

Journal of Forensic and Legal Medicine
Y P Raghavendra BabuRao Lakshmi
Pediatric Neurosurgery
Moncef BerhoumaMoncef Khaldi
Obstetrics and Gynecology
Masakazu TerauchiTaketoshi Maehara
© 2021 Meta ULC. All rights reserved