MR imaging for accurate prediction of outcome after perinatal arterial ischemic stroke: Sooner not necessarily better

European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society
Nienke WagenaarLinda S de Vries

Abstract

Involvement of the corticospinal tracts after perinatal arterial ischemic stroke (PAIS) is strongly correlated with adverse motor outcome. Two full-term infants with PAIS, with two early MRI scans available, are reported. Diffusion weighted imaging (DWI)-MRI, performed within 24 h following onset of seizures and repeated 48 h later, clearly showed restricted diffusion within the middle cerebral artery territory on both MRIs, but clear patterns of signal intensity changes in the descending corticospinal tracts on the second MRI only. Since involvement of the corticospinal tracts is essential for prediction of motor outcome, we may need to reconsider optimal timing of MR imaging for prediction of neurodevelopmental outcome after PAIS.

Citations

Jun 16, 2019·Archives of Disease in Childhood. Fetal and Neonatal Edition·Gemma ArcaAlfredo García-Alix
Nov 20, 2019·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·Andreas WiedemannUNKNOWN Swiss Neuropediatric Stroke Registry Group
Mar 16, 2021·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·Cindy Leal MartinsJoel Fluss

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