MR imaging in the management before surgery of lobular carcinoma of the breast: correlation with pathology

AJR. American Journal of Roentgenology
G N RodenkoD P Flamig

Abstract

Our objective was to investigate the use of MR imaging in preoperative staging and characterization of lobular carcinoma. MR imaging studies and mammographic studies in 20 patients with infiltrating lobular carcinoma were evaluated and correlated with pathology findings on serially sectioned tissue. The MR images and mammograms were reviewed retrospectively by three independent examiners unaware of the clinical, imaging, and pathology findings. The extent of disease found pathologically correlated with that predicted by MR imaging studies in 85% of patients, compared with a 32% correlation (p < .0001) with mammographic studies. Interobserver agreement on lesion morphology and extent of disease was higher for MR imaging (91% and 100%, respectively) than for mammography (64% and 91%, respectively). The retrospective MR readings did not differ from the prospective reports. No false-positive lymphadenopathy was interpreted on MR imaging. Lymph nodes having metastatic lobular carcinoma on the pathology examination were missed on MR imaging in four patients. MR imaging is significantly more accurate than mammography in determining the extent of disease and characterizing the morphology of infiltrating lobular carcinoma. MR imaging ma...Continue Reading

Citations

May 31, 2001·Journal of Magnetic Resonance Imaging : JMRI·K Kinkel, N M Hylton
May 31, 2001·Journal of Magnetic Resonance Imaging : JMRI·S E Harms
Dec 27, 2005·Medical Molecular Morphology·Ritsu KusamaShin-ichi Tsuchiya
Sep 23, 2008·Breast Cancer Research and Treatment·K E PengelK G A Gilhuijs
Sep 19, 2008·La Radiologia medica·G LevriniF Nicoli
Jun 1, 2002·European Journal of Radiology·A A TardivonD Vanel
Apr 13, 2002·Journal of the American College of Surgeons·Richard L Ellis
Jun 1, 2002·Breast Cancer Research and Treatment·C Balu-MaestroR Largillier
Jun 26, 2004·Breast Cancer Research and Treatment·Carla BoetesJelle O Barentsz
Apr 5, 2011·Annals of Oncology : Official Journal of the European Society for Medical Oncology·J HeilH Junkermann
Feb 16, 2005·Current Opinion in Obstetrics & Gynecology·Veronique Cocquyt, Simon Van Belle
Nov 10, 2001·Annual Review of Biomedical Engineering·J KettenbachF A Jolesz
Dec 5, 2008·AJR. American Journal of Roentgenology·Linda Moy, Cecilia L Mercado
Mar 5, 2011·AJR. American Journal of Roentgenology·Amy Argus, Mary C Mahoney
Dec 24, 2010·AJR. American Journal of Roentgenology·Robert L GutierrezConstance D Lehman
Mar 5, 2011·AJR. American Journal of Roentgenology·Amy Argus, Mary C Mahoney
Feb 13, 2001·AJR. American Journal of Roentgenology·S P WeinsteinM Schnall
Apr 18, 2002·AJR. American Journal of Roentgenology·Aliya QayyumRobert J Herfkens
Jan 24, 2003·AJR. American Journal of Roentgenology·Laura LibermanD David Dershaw
Jan 23, 2004·AJR. American Journal of Roentgenology·Janie M LeeMitchell D Schnall
Aug 28, 2012·Radiology·Bruce J HillmanLawrence J Moss
Sep 25, 2001·Radiology·H K Gill, W A Berg
May 9, 2009·Asian Journal of Surgery·Takeshi HanagiriKosei Yasumoto
Aug 10, 2013·Magnetic Resonance Imaging Clinics of North America·Natasha BrasicBonnie N Joe
Jul 26, 2011·Seminars in Ultrasound, CT, and MR·Debra L Monticciolo
Mar 23, 2011·Obstetrics and Gynecology Clinics of North America·Eren D Yeh
May 25, 2010·Magnetic Resonance Imaging Clinics of North America·Eren D Yeh
May 25, 2010·Magnetic Resonance Imaging Clinics of North America·Sara C Gavenonis, Susan Orel Roth
May 25, 2010·Magnetic Resonance Imaging Clinics of North America·Ritse M Mann
Oct 29, 2008·Advances in Surgery·Claire S CooneyTheodore N Tsangaris
Oct 9, 2007·Seminars in Roentgenology·Werner A Kaiser
Jun 15, 2007·Surgical Oncology Clinics of North America·Nora M Hansen, Alicia Growney

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Lobular

Lobular carcinoma is an invasive type of breast cancer in which lobules, areas of the breast that produce milk, undergo malignant transformation. Here is the latest research.