MR imaging of hepatocellular adenomas on genotype-phenotype classification: A report from China

European Journal of Radiology
Heqing WangMengsu Zeng

Abstract

To investigate and compare the MR features between hepatocellular adenoma (HCA) subtypes in China, including preliminary observations on diffusion-weighted imaging (DWI). Thirty-six patients with 39 pathologically proven HCAs underwent gadopentetate dimeglumine enhanced MRI. The morphological and imaging features on T1, T2-weighted, dynamic-enhanced imaging and DWI were retrospectively evaluated and compared between four HCA subtypes, using Kruskal-Wallis test, Fisher's exact test and Dunn-Bonferroni post hoc test. HCA frequently occurred in male (n = 19, 52.8%), lacked an association with oral contraceptives (n = 0), and had a relatively high incidence of coexistent Hepatitis B infection (n = 6, 16.7%). Signals on T1 and T2-weighted imaging, enhancement pattern and intensity, lesion heterogeneity, as well as accompanying findings including lesion steatosis, necrosis or cystic component, central scar, and pseudocapsule were different between HCA subtypes (P < .0001 to P = .019). Apparent diffusion coefficient (ADC) values among HCA subtypes were different as a whole (P = .029), within which β-catenin-mutated HCA had the lowest ADCs; but post hoc comparisons demonstrated no significant differences between groups (P = .066-1.000)...Continue Reading

Citations

Jan 1, 2020·Intractable & Rare Diseases Research·Rishi Philip MathewGavin Low
May 29, 2020·Liver International : Official Journal of the International Association for the Study of the Liver·Anne J KlompenhouwerJan N M Ijzermans
May 21, 2020·European Journal of Gastroenterology & Hepatology·Beverly T RodriguesAmanda J Nicoll
Jun 7, 2019·World Journal of Gastroenterology : WJG·Matteo RenzulliRita Golfieri
Jul 18, 2021·Hepatobiliary & Pancreatic Diseases International : HBPD INT·João M LouroManuela França

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cancer Imaging

Imaging techniques, including CT and MR, have become essential to tumor detection, diagnosis, and monitoring. Here is the latest research on cancer imaging.

Adenoma, Liver Cell

Liver Cell Adenoma or hepatic adenoma is a rare benign tumor. It is associated with birth control use or pregnancy. Discover the latest research on Liver Cell Adenoma here.