MR imaging of infiltrative muscle involvement with Langerhans cell histiocytosis

Clinical Imaging
David A MayWilliam J Frable

Abstract

Langerhans cell histiocytosis (LCH) consists of three clinical syndromes of varying severity resulting from basic cellular defect leading to lipid deposition within histiocytes. Radiologically, bone lesions are similar in all three forms of LCH and are due to bone destruction. An eosinophilic granuloma of the bone can involve skeletal muscle by direct extension from the bone. However, skeletal muscle involvement is rare and is not reported on MR imaging previously in the English literature. Our case not only shows biopsy-proven muscle involvement by LCH but also reports the first diffuse nodular pattern of muscle involvement by LCH.

References

Oct 1, 1995·Skeletal Radiology·M MatsuoT Sugai
Apr 1, 1997·Radiology·V S LeeR E Coleman
May 5, 1999·AJR. American Journal of Roentgenology·F S ChewS B Keel
Jun 16, 2000·Skeletal Radiology·T Yamamoto, K Mizuno
Oct 25, 2000·Radiographics : a Review Publication of the Radiological Society of North America, Inc·D A MayB J Manaster

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Citations

Aug 19, 2009·Pediatric Blood & Cancer·Désirée GavhedJan-Inge Henter
Nov 26, 2010·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Chia-Hsing LuRuey-Sheng Chang
Sep 19, 2012·Polski przeglad chirurgiczny·Pantea TajikHazhir Javaherizadeh
Jul 24, 2014·Arquivos de neuro-psiquiatria·Larissa Barcessat GabbayLeandro Tavares Lucato
Jul 16, 2008·Pediatric Blood & Cancer·Ingrid Van't HooftJan-Inge Henter
Mar 18, 2021·Revista española de patología : publicación oficial de la Sociedad Española de Anatomía Patológica y de la Sociedad Española de Citología·Isidro MachadoAntonio Llombart-Bosch

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