MR lesion detection in a breast cancer population

Journal of Magnetic Resonance Imaging : JMRI
I M ObdeijnM Oudkerk

Abstract

Implementation of MR imaging of the breast as an extension of the existing imaging modalities in the diagnosis of breast cancer was evaluated in a university cancer center, MR imaging of the breast was performed in 54 patients, in whom the MR results were compared with the triple test (the combination of clinical examination, mammographic evaluation, and cytology) and the final histological diagnosis. MR imaging of the breast depicted 30 of the 33 malignancies (sensitivity, 91%). In two of the malignancies, the carcinoma was clinically and mammographically occult. For the three patients with a false-negative MRI diagnosis, the conventional mammography showed suspicions clustered microcalcifications as a sign of in situ carcinoma. For seven patients, MR imaging of the breast incorrectly suggested the presence of a malignant lesion (specificity, 67%). To improve MR specificity, we perform MR-guided ultrasonographic fine-needle aspiration biopsy (FNAB). Although MR imaging of the breast is a highly sensitive examination, conventional x-ray mammography remains the most efficient imaging modality in the diagnosis of breast cancer. In our patient population, MR imaging of the breast had additional value for women with mammographicall...Continue Reading

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Citations

May 31, 2001·Journal of Magnetic Resonance Imaging : JMRI·T B Julian
Sep 6, 2001·Journal of Magnetic Resonance Imaging : JMRI·E SchneiderD Ballon
Feb 16, 2005·European Radiology·Eija PääkköTarja Rissanen
Jan 12, 2011·Breast Cancer Research and Treatment·Lidia Rosi MedeirosMaria Inês Rosa
Apr 17, 1999·European Journal of Obstetrics, Gynecology, and Reproductive Biology·H G Brunner, M J Ligtenberg
Jun 1, 1997·Breast Cancer Research and Treatment·M M Tilanus-LinthorstM Oudkerk
Nov 18, 2000·Breast Cancer Research and Treatment·M M Tilanus-LinthorstM Oudkerk
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Apr 5, 2000·AJR. American Journal of Roentgenology·I M ObdeijnM Oudkerk
Nov 21, 2007·Radiology·Nicky H G M PetersPetra H M Peeters
Sep 26, 2003·Journal of Magnetic Resonance Imaging : JMRI·Milica MedvedGregory S Karczmar
Apr 28, 1999·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·V BongersP P van Rijk

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