PMID: 8946347Dec 1, 1996Paper

MR spectroscopic imaging and diffusion-weighted MRI for early detection of kainate-induced status epilepticus in the rat

Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine
T EbisuA A Maudsley

Abstract

Previous studies have shown that reduction of N-acetyl-aspartate (NAA) is correlated with the degree of neuronal loss at 3 days after kainate-induced status epilepticus in the rat. In this study, magnetic resonance spectroscopic imaging (MRSI), measurement of NAA and lactate, T2-weighted MRI, and diffusion-weighted MRI were used to study early alterations in rat piriform cortex at 12 and 26 h after kainate administration. The major findings are that decreased NAA signal, increased lactate signal, and decreased apparent diffusion coefficient (ADC) were observed at 12 h, with little evidence of histological and T2-weighted MRI changes. These results support the hypothesis that NAA, lactate signals, and ADC provide sensitive methods for detection of early and minimal brain damage in vivo.

References

May 1, 1992·Stroke; a Journal of Cerebral Circulation·H BenvenisteG A Johnson
May 1, 1992·Epilepsy Research·I A LangmoenJ Berg-Johnsen
Jan 1, 1992·Magnetic Resonance Imaging·A A MaudsleyM W Weiner
Jul 1, 1991·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·M D KingM Doran
May 1, 1990·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·M E MoseleyP R Weinstein
Jan 1, 1989·Neuroscience and Biobehavioral Reviews·D L Birken, W H Oldendorf
Dec 1, 1988·Annals of Neurology·R N Auer, B K Siesjö
Sep 1, 1972·Journal of Neurochemistry·J V Nadler, J R Cooper
Jul 1, 1983·Journal of Neurochemistry·J T Coyle
Oct 1, 1995·Stroke; a Journal of Cerebral Circulation·M WickJ Frahm
Feb 1, 1995·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·J ZhongJ C Gore
May 1, 1994·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·K KamadaT Nakada
Jun 1, 1994·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·A A MaudsleyM W Weiner
Dec 1, 1993·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·S W Provencher
May 1, 1994·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·T EbisuA A Maudsley
Nov 1, 1993·Journal of Magnetic Resonance Imaging : JMRI·T EbisuT Higuchi
Feb 1, 1994·Stroke; a Journal of Cerebral Circulation·T BackK A Hossmann
Aug 1, 1993·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·J ZhongJ C Gore
Nov 1, 1995·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·N De StefanoD L Arnold
May 1, 1996·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·W D RooneyA A Maudsley

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Citations

Jul 14, 2000·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·W T LeeC Chang
Apr 3, 2001·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Y BitoS Naruse
Mar 9, 2004·Brain Research. Brain Research Reviews·Amy J Ross, Perminder S Sachdev
Aug 14, 2003·Brain Research·Daisuke HasegawaKiyotaka Hashizume
Jan 15, 1999·Magnetic Resonance Imaging·U C WieshmannS D Shorvon
Mar 10, 2000·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·D L SchomerJ Ives
Mar 22, 2008·AJR. American Journal of Roentgenology·James M ProvenzaleDarrell V Lewis
Feb 4, 2014·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·Sandy R ShultzRuben I Kuzniecky
Sep 1, 2009·Brain Research·Natalie M ZahrAdolf Pfefferbaum
Jan 17, 2012·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Shai ShrotYoram Cohen
Sep 24, 2004·Lancet Neurology·Sheryl R HautSolomon L Moshé
Oct 21, 2006·Röntgenpraxis; Zeitschrift für radiologische Technik·Janine RennertOliver Ganslandt
Aug 25, 2004·Neuroimaging Clinics of North America·Fergus J Rugg-Gunn, Mark R Symms
Apr 24, 2015·Toxicological Sciences : an Official Journal of the Society of Toxicology·Serguei LiachenkoJoseph Hanig
Mar 13, 2014·Epilepsy & Behavior : E&B·A M CartagenaS M Mirsattari
Jul 8, 2016·Journal of Magnetic Resonance Imaging : JMRI·Serguei Liachenko, Jaivijay Ramu
May 29, 2000·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·T N SagerH Laursen
Feb 27, 2001·Brain : a Journal of Neurology·S H ErikssonJ S Duncan
Apr 17, 2003·British Medical Bulletin·Mark F LythgoeNeil G Harris
Jun 17, 1998·Stroke; a Journal of Cerebral Circulation·S LiachenkoY Xu
Jul 27, 2007·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·W A GomesH P Hetherington
May 29, 2008·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·H RabesonD Graveron-Demilly
Apr 29, 2005·Epilepsia·Regula S BriellmannGraeme D Jackson
May 8, 2021·Brain & Development·Yumeng ZhangMuneaki Matsuo

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