MR Thermometry in Cerebrovascular Disease: Physiologic Basis, Hemodynamic Dependence, and a New Frontier in Stroke Imaging.

AJNR. American Journal of Neuroradiology
S Dehkharghani, D Qiu

Abstract

The remarkable temperature sensitivity of the brain is widely recognized and has been studied for its role in the potentiation of ischemic and other neurologic injuries. Pyrexia frequently complicates large-vessel acute ischemic stroke and develops commonly in critically ill neurologic patients; the profound sensitivity of the brain even to minor intraischemic temperature changes, together with the discovery of brain-to-systemic as well as intracerebral temperature gradients, has thus compelled the exploration of cerebral thermoregulation and uncovered its immutable dependence on cerebral blood flow. A lack of pragmatic and noninvasive tools for spatially and temporally resolved brain thermometry has historically restricted empiric study of cerebral temperature homeostasis; however, MR thermometry (MRT) leveraging temperature-sensitive nuclear magnetic resonance phenomena is well-suited to bridging this long-standing gap. This review aims to introduce the reader to the following: 1) fundamental aspects of cerebral thermoregulation, 2) the physical basis of noninvasive MRT, and 3) the physiologic interdependence of cerebral temperature, perfusion, metabolism, and viability.

References

Jan 1, 1979·The Journal of Physiology·M Cabanac, M Caputa
May 1, 1979·Scientific American·M A Baker
Jul 1, 1975·Journal of Applied Physiology·T V McCaffreyR D Wurster
Mar 1, 1991·Annals of Neurology·W J Powers
Sep 1, 1990·Journal of Neuropathology and Experimental Neurology·W D DietrichI Valdes
May 1, 1990·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·H MinamisawaB K Siesjö
May 1, 1990·Stroke; a Journal of Cerebral Circulation·H MinamisawaB K Siesjö
Sep 1, 1990·Stroke; a Journal of Cerebral Circulation·W D DietrichY Loor
Aug 1, 1989·Stroke; a Journal of Cerebral Circulation·R BustoM D Ginsberg
Dec 1, 1987·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·R BustoM D Ginsberg
Aug 1, 1968·The American Journal of Physiology·J N Hayward, M A Baker
Jun 1, 1972·Journal of Applied Physiology·M A BakerJ P Meehan
Apr 1, 1968·Life Sciences·M A Baker, J N Hayward
May 1, 1983·Medical Physics·D L ParkerL Fussell
Jan 1, 1982·Annual Review of Physiology·M A Baker
Sep 1, 1995·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·J De Poorter
Jun 1, 1995·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·E B CadyA Lorek
Jan 1, 1995·Acta neurochirurgica·J VerlooyP Selosse
Aug 1, 1994·The American Journal of Physiology·G Kuhnen, C Jessen
Sep 1, 1993·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·M Cabanac
Dec 1, 1995·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Y IshiharaY Suzuki
Jan 1, 1996·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·K KurodaY Suzuki
Apr 1, 1997·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·R CorbettP Weatherall
Nov 14, 1997·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·K KurodaF A Jolesz
Feb 24, 1998·Stroke; a Journal of Cerebral Circulation·M D Ginsberg, R Busto
Jul 9, 1998·Journal of Applied Physiology·E H Wissler
Oct 1, 1998·European Journal of Applied Physiology and Occupational Physiology·D A Nelson, S A Nunneley
May 7, 1999·Stroke; a Journal of Cerebral Circulation·C P DerdeynW J Powers
Feb 19, 2000·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·K KurodaF A Joles
Jun 22, 2000·Proceedings of the National Academy of Sciences of the United States of America·D A YablonskiyM E Raichle
Oct 3, 2000·Neurosurgery·M M KilpatrickD W Marion
Jul 14, 2001·Acta Neurochirurgica. Supplement·J InamasuT Kawase
Mar 2, 2002·Brain : a Journal of Neurology·Colin P DerdeynWilliam J Powers
May 29, 2003·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Hyung Soo HanMidori A Yenari
Aug 6, 2003·Surgical Neurology·Yasunari OtawaraMichiyasu Suzuki
Oct 1, 1960·The American Journal of Cardiology·K B WOLFE
Aug 24, 2004·Journal of Applied Physiology·Christopher M CollinsRobert Turner
Sep 9, 2005·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Kagayaki Kuroda
Sep 9, 2005·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·S K HekmatyarN Bansal

❮ Previous
Next ❯

Citations

Oct 10, 2020·Brain Communications·Seena DehkharghaniRaul G Nogueira

❮ Previous
Next ❯

Related Concepts

Related Feeds

Brain Ischemia

Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. Discover the latest research on brain ischemia here.

Brain Injury & Trauma

brain injury after impact to the head is due to both immediate mechanical effects and delayed responses of neural tissues.

Acute Stroke

A stroke occurs when blood supply to the brain is interrupted depriving the brain of oxygen and nutrients. This feed focuses cerebrovascular accidents including ischemic and paralytic stroke.

Related Papers

La Revue du praticien
Julien Wyplosz
Acta chirurgica Belgica
J P Flamand
Casopís lékar̆ů c̆eských
F Kaderávek
International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group
Lukas WinterThoralf Niendorf
© 2021 Meta ULC. All rights reserved