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MRI analysis of mGluR5 and mGluR1 antagonists, MTEP and R214127 in the cerebral forebrain of awake, conscious rats

Neuroscience Letters

Oct 22, 2011

Laszlo SimonDenes V Agoston

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Abstract

Metabotropic glutamate receptors mGluR5 and mGluR1 mediate key neuropsychiatric functions in health and disease and their antagonists hold promise to treat anxiety, depression, inflammation, and neuropathic pain. Pharmacological magnetic resonance imaging (phMRI) using a functional MRI ...read more

Mentioned in this Paper

Pyridines
Magnetic Resonance Imaging
Neostriatum
Acclimatization
Blood Vessel
Antagonist Muscle Action
Quinolines
Brain
Receptors, Metabotropic Glutamate
Cell Respiration
Paper Details
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  • References44
  • Citations2
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MRI analysis of mGluR5 and mGluR1 antagonists, MTEP and R214127 in the cerebral forebrain of awake, conscious rats

Neuroscience Letters

Oct 22, 2011

Laszlo SimonDenes V Agoston

PMID: 22015763

DOI: 10.1016/j.neulet.2011.10.010

Abstract

Metabotropic glutamate receptors mGluR5 and mGluR1 mediate key neuropsychiatric functions in health and disease and their antagonists hold promise to treat anxiety, depression, inflammation, and neuropathic pain. Pharmacological magnetic resonance imaging (phMRI) using a functional MRI ...read more

Mentioned in this Paper

Pyridines
Magnetic Resonance Imaging
Neostriatum
Acclimatization
Blood Vessel
Antagonist Muscle Action
Quinolines
Brain
Receptors, Metabotropic Glutamate
Cell Respiration

Feeds With Similar Papers

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The extracellular space (ECS) in brain occupies approximately twenty percent of the brain volume and is dynamic and highly regulated. Here is the latest research on ECS in the brain.

Magnetic Resonance Imaging: Brain (MDS)

Magnetic Resonance Imaging (MRI) is a non-invasive imaging technique that uses a powerful magnetic field and radio waves to generate images of the area of interest. MRI of the brain is commonly performed to visualize the brain and related structures in detail. Discover the latest research of MRI and the brain here.

Related Papers

Paper Details
References
  • References44
  • Citations2
12345

Download from

Publisher
PubMed
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