MRI and CT contrast media extravasation: A systematic review

Medicine
Ashkan Heshmatzadeh BehzadiMartin R Prince

Abstract

This systematic review combines data from multiple papers on contrast media extravasation to identify factors contributing to increased extravasation risk. Data were extracted from 17 papers reporting 2191 extravasations in 1,104,872 patients (0.2%) undergoing computed tomography (CT) or magnetic resonance imaging (MRI). Extravasation rates were 0.045% for gadolinium-based contrast agents (GBCA) and nearly 6-fold higher, 0.26% for iodinated contrast agents. Factors associated with increased contrast media extravasations included: older age, female gender, using an existing intravenous (IV) instead of placing a new IV in radiology, in-patient status, use of automated power injection, high injection rates, catheter location, and failing to warm up the more viscous contrast media to body temperature. Contrast media extravasation is infrequent but nearly 6 times less frequent with GBCA for MRI compared with iodinated contrast used in CT.

References

Apr 1, 1992·AJR. American Journal of Roentgenology·G D PondK A McAleese
Apr 1, 1991·The British Journal of Surgery·G B Lewis, J F Hecker
Nov 1, 1986·Journal of Computer Assisted Tomography·W P ShumanA A Moss
Jan 1, 1993·AJR. American Journal of Roentgenology·M MemoloR J Zagoria
Mar 1, 1993·British Journal of Plastic Surgery·D T Gault
May 25, 2001·AJR. American Journal of Roentgenology·S T CochranJ W Sayre
Feb 28, 2002·European Radiology·Marie-France BellinPhilippe Grenier
Oct 19, 2002·European Radiology·Marie-France BellinUNKNOWN Contrast Media Safety Committee Of The European Society Of Urogenital Radiology
Mar 24, 2005·Medical Principles and Practice : International Journal of the Kuwait University, Health Science Centre·Tareq SinanMehraj Sheikh
Aug 2, 2007·The American Journal of Nursing·Lynn Hadaway
Jul 8, 2010·Surgical and Radiologic Anatomy : SRA·Brian H EisnerMarshall L Stoller
Jul 16, 2010·JAMA : the Journal of the American Medical Association·David J Brenner, Hedvig Hricak
Sep 23, 2010·AJR. American Journal of Roentgenology·Susanne WienbeckKai U Juergens
Jan 25, 2011·AJR. American Journal of Roentgenology·Martin R PrincePaula W Brill
Apr 14, 2012·Journal of Medical Imaging and Radiation Oncology·Roger J KingstonMinh Truong
Oct 16, 2015·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Katrina R BeckettJessica M Langer
Apr 4, 2016·Abdominal Radiology·William R MaschMatthew S Davenport
May 14, 2016·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Elizabeth S RoweJames S Barnett
Oct 18, 2016·Topics in Magnetic Resonance Imaging : TMRI·Ashkan Heshmatzadeh Behzadi, Martin R Prince

❮ Previous
Next ❯

Citations

Nov 7, 2019·Annals of Plastic Surgery·Sameer MassandT Shane Johnson
Mar 12, 2020·Canadian Association of Radiologists Journal = Journal L'Association Canadienne Des Radiologistes·Shobhit MathurNoah G Ditkofsky
Jan 11, 2020·Emergency Radiology·Jeffrey R StowellCarl Mitchell
May 15, 2020·Clinical Nuclear Medicine·Jiali TangFuqiang Shao
Mar 18, 2020·Emergency Radiology·Garvit D Khatri, Jeffrey D Robinson
Jan 24, 2020·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Lenhard PennigJonas Doerner
Sep 3, 2020·Nanomaterials·Sarkar Siddique, James C L Chow
Mar 7, 2020·Abdominal Radiology·Ryan Ward, Andrei S Purysko
Nov 21, 2020·Current Hepatology Reports·Jan PetrasekNicole E Rich
Sep 21, 2021·The British Journal of Radiology·Ioannis VlahosRick R Layman

❮ Previous
Next ❯

Software Mentioned

ACROBAT
Google Scholar
Cochrane Risk of Bias Assessment Tool

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.