MRI and CT findings of the giant cell tumors of the skull; five cases and a review of the literature

European Journal of Radiology
Nobuo KashiwagiHironobu Nakamura

Abstract

To investigate CT and MR findings of giant cell tumors (GCTs) of the skull, an unusual site for such tumors. CT and MR features of five histologically proven giant cell tumors of the skull were retrospectively reviewed. We also reviewed 22 cases in the literature that included MR or CT findings. Three of the tumors originated from the temporal bone with predominantly medial extension, and the other two were centered in the body of the sphenoid bone and featured symmetrical soft tissue extension. CT images with bone window settings showed reactive bone changes for all three tumors of the temporal bone, suggesting slow growth for example, an expanded intradiploic space, expansive remodelling and development of foci of pressure erosion. GCTs of the sphenoid bone showed purely osteolytic changes without remodelling. Although the MR signals and enhancement patterns varied, all the tumors of the temporal bone had a markedly low intensity area on T2-weighted images, which was not seen in the tumors of the sphenoid bone. The findings for our cases generally corresponded to those reported in the literature. Giant cell tumors of the skull have two preferential sites and may have characteristic tendencies as to their extent. Bone changes ...Continue Reading

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Citations

Nov 30, 2011·Neurologia Medico-chirurgica·Yuuta KamoshimaKiyohiro Houkin
May 19, 2010·Journal of Cancer Research and Therapeutics·Ranjana BandyopadhyayM M Ray
Jul 4, 2012·Clinical Radiology·T A AbeleD B Mendelsohn
May 9, 2015·World Journal of Surgical Oncology·Lili YangLi Bie
Sep 17, 2013·European Journal of Radiology·Ming-Jue SiWei-Bin Zhang
Oct 30, 2016·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Yi ShenJian Sun
May 20, 2016·Brain Tumor Research and Treatment·Dae Hwan Kim, Chang Ki Hong
Oct 12, 2017·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Diana P RodriguezBernadette L Koch
Sep 18, 2013·Journal of Neuro-oncology·Zhenyu ZhangPing Zhong
Feb 18, 2017·Ophthalmology and Therapy·Peter H TangAli Mokhtarzadeh

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