MRI Assessment of Diastolic and Systolic Intraventricular Pressure Gradients in Heart Failure

Current Heart Failure Reports
Snigdha JainJulio A Chirinos

Abstract

A deep phenotypic characterization of heart failure (HF) is important for a better understanding of its pathophysiology. In particular, novel noninvasive techniques for the characterization of functional abnormalities in HF with preserved ejection fraction are currently needed. While echocardiography is widely used to assess ventricular function, standard echocardiographic techniques provide a limited understanding of ventricular filling. The application of fluid dynamics theory, along with assessments of flow velocity fields in multiple dimensions in the ventricle, can be used to assess intraventricular pressure gradients (IVPGs), which in turn may provide valuable insights into ventricular diastolic and systolic function. Advances in imaging techniques now allow for accurate estimations of systolic and diastolic IVPGs, using noninvasive methods that are easily applicable in clinical research. In this review, we describe the basic concepts regarding intraventricular flow measurements and the derivation of IVPGs. We also review existing literature exploring the role of IVPGs in HF.

References

Jan 1, 1992·Annals of Biomedical Engineering·J D Thomas, A E Weyman
May 1, 1992·Journal of Magnetic Resonance Imaging : JMRI·L SøndergaardO Henriksen
Aug 1, 1992·Journal of the American College of Cardiology·P BrunJ L Dubois-Rande
Jan 1, 1990·Progress in Cardiovascular Diseases·E L YellinR W Frater
Mar 15, 1990·Journal of the American College of Cardiology·A Pasipoularides
Jan 1, 1989·Journal of the American College of Cardiology·J D Thomas, A E Weyman
Aug 1, 1987·Circulation Research·A PasipoularidesW E Craig
Apr 1, 1986·Journal of the American College of Cardiology·P J CurrieA J Tajik
Mar 1, 1972·Cardiovascular Research·B J Bellhouse
Oct 1, 1984·The American Journal of Cardiology·S D VaskoH D Allen
Jan 1, 1980·Catheterization and Cardiovascular Diagnosis·H L FalsettiJ A Cramer
Mar 1, 1980·British Heart Journal·L HatleA Tromsdal
Jul 1, 1995·Medical Physics·D B PlewesI Soutar
Nov 1, 1994·Journal of Magnetic Resonance Imaging : JMRI·S N Urchuk, D B Plewes
Nov 1, 1995·Journal of Magnetic Resonance Imaging : JMRI·S N Urchuk, D B Plewes
Nov 1, 1995·Journal of Magnetic Resonance Imaging : JMRI·S N Urchuk, D B Plewes
Oct 1, 1996·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·G Z YangD N Firmin
Nov 1, 1996·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·L WigströmB Wranne
Sep 1, 1995·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·H TsujinoK Iinuma
Jul 14, 2000·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·J P TasuJ Bittoun
Aug 10, 2000·Journal of Magnetic Resonance Imaging : JMRI·J M TyszkaJ M Silverman
Apr 27, 2001·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·T EbbersM Karlsson
May 18, 2001·American Journal of Physiology. Heart and Circulatory Physiology·N L GreenbergJ D Thomas

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