MRI-based score to predict surgical difficulty in patients with rectal cancer

The British Journal of Surgery
L EscalP Rouanet

Abstract

Rectal cancer surgery is technically challenging and depends on many factors. This study evaluated the ability of clinical and anatomical factors to predict surgical difficulty in total mesorectal excision. Consecutive patients who underwent total mesorectal excision for locally advanced rectal cancer in a laparoscopic, robotic or open procedure after neoadjuvant treatment, between 2005 and 2014, were included in this retrospective study. Preoperative clinical and MRI data were studied to develop a surgical difficulty grade. In total, 164 patients with a median age of 61 (range 26-86) years were considered to be at low risk (143, 87·2 per cent) or high risk (21, 12·8 per cent) of surgical difficulty. In multivariable analysis, BMI at least 30 kg/m2 (P = 0·021), coloanal anastomosis (versus colorectal) (P = 0·034), intertuberous distance less than 10·1 cm (P = 0·041) and mesorectal fat area exceeding 20·7 cm2 (P = 0·051) were associated with greater surgical difficulty. A four-item score (ranging from 0 to 4), with each item (BMI, type of surgery, intertuberous distance and mesorectal fat area) scored 0 (absence) or 1 (presence), is proposed. Patients can be considered at high risk of a difficult or challenging operation if they...Continue Reading

References

Jan 23, 2004·AJR. American Journal of Roentgenology·Gina BrownRichard J Heald
Apr 30, 2005·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·K M BoyleD Burke
Feb 28, 2006·Journal of the American College of Surgeons·Tsuyoshi KonishiHirokazu Nagawa
Oct 13, 2006·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·G SalernoB J Moran
Apr 20, 2007·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·S JeyarajahUNKNOWN Leicester Colorectal Specialist Group
Jan 11, 2008·International Journal of Colorectal Disease·A A F A VeenhofM A Cuesta
Jul 8, 2009·Diseases of the Colon and Rectum·Kirsten M BoyleDermot Burke
Nov 3, 2010·Annals of Surgery·Frederic BretagnolUNKNOWN French Research Group of Rectal Cancer Surgery (GRECCAR)
Nov 26, 2010·Annals of Surgery·Daniel LeonardUNKNOWN PROCARE, a multidisciplinary Belgian Project on Cancer of the Rectum
Mar 13, 2013·Diseases of the Colon and Rectum·Philippe RouanetPierre-Emmanuel Colombo
Apr 12, 2013·Diseases of the Colon and Rectum·Eric RullierChristophe Laurent
Oct 15, 2013·Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society·David-Olivier D AzulayJim Graham
Feb 27, 2014·World Journal of Surgical Oncology·Chu WangWeidong Pan
Aug 8, 2014·Diseases of the Colon and Rectum·M M BertrandP Rouanet

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Citations

Nov 15, 2018·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·N de'AngelisUNKNOWN EuMaRCS Study Group
Feb 12, 2019·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·P RouanetM Gomez Ruiz
Feb 11, 2020·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·Shenghui HuangPan Chi
Oct 1, 2019·Diseases of the Colon and Rectum·Nathan J CurtisNader K Francis
Jul 16, 2020·Techniques in Coloproctology·Dimitri KrizzukSteven D Wexner
Nov 28, 2020·Langenbeck's Archives of Surgery·Pere PlanellasAntoni Codina-Cazador
Apr 10, 2021·Diseases of the Colon and Rectum·Philippe Rouanet
Aug 3, 2021·International Journal of Colorectal Disease·Jonathan S Y HongMichael J Solomon
Aug 22, 2021·Updates in Surgery·I MontroniUNKNOWN AIMS Academy clinical research network
May 5, 2021·Minerva Surgery·Blanche Teste, Eric Rullier

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