Abstract
Combined hepatocellular-cholangiocarcinoma (cHCC-CC) is a rare primary liver tumor, which has overlapping imaging features with mass forming intra-hepatic cholangiocarcinoma (ICC) and hepatocellular carcinoma (HCC). Previous studies reported imaging features more closely resemble ICC and the aim of our study was to examine the differential MRI features of cHCC-CC and ICC with emphasis on enhancement pattern observations of gadolinium enhanced MRI. Institutional review board approval with consent waiver was obtained for this retrospective bi-centric study. Thirty-three patients with pathologically proven cHCC-CC and thirty-eight patients with pathologically proven ICC, who had pre-operative MRI, were identified. MRI images were analyzed for tumor location and size, T1 and T2 signal characteristics, the presence/absence of: cirrhosis, intra-lesional fat, hemorrhage/hemosiderin, scar, capsular retraction, tumor thrombus, biliary dilatation, degree of arterial enhancement, enhancement pattern, pseudocapsule and washout. Associations between MRI features and tumor type were examined using the Fisher's exact and chi-square tests. Strong arterial phase enhancement and the presence of: washout, washout and progression, intra-lesional f...Continue Reading
References
Nov 1, 1993·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·K AokiT Kosuge
Apr 5, 2002·Cancer·William R JarnaginDavid Klimstra
Aug 13, 2003·Japanese Journal of Clinical Oncology·Yoshiko YanoMasatoshi Makuuchi
Aug 4, 2004·Journal of Hepatology·Dominique Cazals-HatemJessica Zucman-Rossi
Feb 11, 2005·American Journal of Surgery·Kwang Cheol KohHong Joo Kim
Sep 26, 2006·Surgery Today·Won-Suk LeeJae-Won Joh
Feb 10, 2007·International Journal of Gastrointestinal Cancer·Vishal BhagatRenuka Iyer
Nov 3, 2007·European Journal of Radiology·Seong Hyun KimCheol Keun Park
Feb 21, 2008·International Journal of Clinical Practice·W T Kassahun, J Hauss
Apr 8, 2009·Abdominal Imaging·Tae Yeon JeonHyo K Lim
Jun 23, 2009·AJR. American Journal of Roentgenology·Yong Eun ChungMyeong-Jin Kim
Apr 28, 2010·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·C PanjalaD M Harnois
Mar 26, 2011·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Gonzalo SapisochinFrancis Y Yao
Aug 24, 2011·Journal of Korean Medical Science·Ho Sung ParkWoo Sung Moon
Mar 28, 2012·Annals of Surgical Oncology·Xin YinJia Fan
Jun 26, 2012·Journal of Magnetic Resonance Imaging : JMRI·Jiyoung HwangHyun Chul Rhim
Jul 12, 2012·Journal of Magnetic Resonance Imaging : JMRI·Rafael O P de CamposJohn T Woosley
Jul 26, 2013·AJR. American Journal of Roentgenology·Kathryn J FowlerChristine O Menias
Jan 21, 2014·Annals of Surgery·G SapisochinR Charco
Apr 30, 2014·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Mattia GaranciniVittorio Giardini
Dec 6, 2014·Hepatobiliary & Pancreatic Diseases International : HBPD INT·Seung Duk LeeEun Kyung Hong
May 9, 2015·Abdominal Imaging·Michael L WellsLewis R Roberts
Feb 13, 2016·AJR. American Journal of Roentgenology·Theodora A PotretzkeKathryn J Fowler
Jan 1, 2014·European Journal of Radiology Open·Suresh MaximinNeeraj Lalwani
Citations
Jul 25, 2019·The American Journal of Gastroenterology·Daryl RamaiDouglas G Adler
May 29, 2020·Radiology and Oncology·Vincenza GranataAntonella Petrillo
Jul 24, 2020·Journal of Magnetic Resonance Imaging : JMRI·Jae Hyun KimJeong Min Lee
Aug 5, 2020·European Radiology·Xiaoyang LiuKartik S Jhaveri
Aug 14, 2020·Aging·Tao WangWentao Wang
Oct 31, 2018·Clinical Journal of Gastroenterology·Yuka FutsukaichiIchiro Yasuda
May 8, 2020·Abdominal Radiology·Seung-Seob KimMyeong-Jin Kim
Aug 27, 2018·Abdominal Radiology·Hsien Min LowCher Heng Tan
Oct 28, 2019·European Radiology·Tyler J FraumKathryn J Fowler
Dec 29, 2020·Frontiers in Oncology·Tao WangWentao Wang
Dec 15, 2020·Journal of the American College of Surgeons·Leigh Anne DagefordeMaria B Majella Doyle
Mar 1, 2020·Annals of Hepatology·Atsuyuki IkedaHiroyuki Kokuryu
Jan 26, 2021·European Radiology·Jie YangAndrej Lyshchik
Nov 18, 2020·Current Problems in Diagnostic Radiology·Abdul RazikArun Kumar Gupta
Dec 29, 2020·World Journal of Gastroenterology : WJG·Jie YangQiang Lu
Feb 26, 2021·Current Problems in Diagnostic Radiology·Sravanthi Mantripragada, Ashish Chawla
Jan 4, 2022·Abdominal Radiology·Si Min ChiowHsien Min Low