MRI features of combined hepatocellular- cholangiocarcinoma versus mass forming intrahepatic cholangiocarcinoma

Cancer Imaging : the Official Publication of the International Cancer Imaging Society
Jennifer SammonKartik Jhaveri

Abstract

Combined hepatocellular-cholangiocarcinoma (cHCC-CC) is a rare primary liver tumor, which has overlapping imaging features with mass forming intra-hepatic cholangiocarcinoma (ICC) and hepatocellular carcinoma (HCC). Previous studies reported imaging features more closely resemble ICC and the aim of our study was to examine the differential MRI features of cHCC-CC and ICC with emphasis on enhancement pattern observations of gadolinium enhanced MRI. Institutional review board approval with consent waiver was obtained for this retrospective bi-centric study. Thirty-three patients with pathologically proven cHCC-CC and thirty-eight patients with pathologically proven ICC, who had pre-operative MRI, were identified. MRI images were analyzed for tumor location and size, T1 and T2 signal characteristics, the presence/absence of: cirrhosis, intra-lesional fat, hemorrhage/hemosiderin, scar, capsular retraction, tumor thrombus, biliary dilatation, degree of arterial enhancement, enhancement pattern, pseudocapsule and washout. Associations between MRI features and tumor type were examined using the Fisher's exact and chi-square tests. Strong arterial phase enhancement and the presence of: washout, washout and progression, intra-lesional f...Continue Reading

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Citations

Jul 25, 2019·The American Journal of Gastroenterology·Daryl RamaiDouglas G Adler
Jul 24, 2020·Journal of Magnetic Resonance Imaging : JMRI·Jae Hyun KimJeong Min Lee
Oct 31, 2018·Clinical Journal of Gastroenterology·Yuka FutsukaichiIchiro Yasuda
Dec 15, 2020·Journal of the American College of Surgeons·Leigh Anne DagefordeMaria B Majella Doyle
Nov 18, 2020·Current Problems in Diagnostic Radiology·Abdul RazikArun Kumar Gupta
Feb 26, 2021·Current Problems in Diagnostic Radiology·Sravanthi Mantripragada, Ashish Chawla
Jan 4, 2022·Abdominal Radiology·Si Min ChiowHsien Min Low

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