MRI features of renal cell carcinoma that predict favorable clinicopathologic outcomes

AJR. American Journal of Roentgenology
Ankur M DoshiHersh Chandarana

Abstract

The purpose of this article is to determine whether MRI features of renal cell carcinoma (RCC), such as enhancing solid component and T1 signal intensity, are associated with clinicopathologic outcomes. This retrospective study included 241 RCCs in 230 patients who underwent preoperative MRI, had pathologic analysis results available, and were monitored for at least 3 months. A radiologist assessed tumor features on MRI, including unenhanced T1 signal relative to renal cortex and the percentage of solid enhancing components. The electronic medical record or follow-up images were reviewed to assess for the development of local recurrence or metastases. Statistical analysis was performed to correlate imaging features at MRI with pathologic and clinical outcome. The following tumor features were observed: predominantly cystic morphologic features (defined as solid component≤25%, n=33), solid component greater than 25% (n=208), T1 hypointensity (n=97), and T1 intermediate intensity or hyperintensity (n=144). Local recurrence or metastases were observed in 14 patients. Compared with T1-intermediate or -hyperintense lesions, T1-hypointense RCCs were more likely to be low stage (90.7% vs 74.3%; p=0.001) and low grade (78.9% vs 41.8%; ...Continue Reading

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Citations

May 8, 2016·Abdominal Radiology·Nicole M Hindman
Jun 8, 2017·The British Journal of Radiology·Massimo GaliaRoberto Lagalla
Mar 13, 2019·AJR. American Journal of Roentgenology·Hiram ShaishNicole M Hindman
Jun 5, 2016·Current Opinion in Urology·Katherine M Krajewski, Atul B Shinagare
Nov 29, 2019·Radiology. Imaging Cancer·Winston B JoeAndrew J Gunn

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