PMID: 9187473Jun 1, 1997Paper

MRI findings and sensorimotor development in infants with bilateral spastic cerebral palsy

Brain & Development
G CioniR Canapicchi

Abstract

The correlation between MRI findings and sensorimotor development was investigated in a group of 48 infants with bilateral spastic cerebral palsy (CP). The ages at MRI examination and cognitive assessment were fairly homogeneous (mean 15 months and 17 months, respectively). The following MRI parameters were scored: size of lateral ventricles, extension of white matter lesions and of white matter reduction, thinning of corpus callosum, presence and size of cystic areas, dimension of subarachnoid spaces and presence of cortical abnormalities. Cognitive assessment included Griffiths Developmental Scales and Uzgiris-Hunt Scales. The patients were subdivided into six classes according to intellectual level (DSM-III-R). For the whole group a highly significant correlation was found between all MRI parameters and the level of cognitive development. This result was probably due to the inclusion of 14 untestable, severely mentally retarded infants, who showed very severe MRI abnormalities. However, when the untestable infants were excluded from the analysis, it was the presence of cysts and the entity of white matter reduction that correlated with both Griffiths Scales and Uzgiris-Hunt Scales. These results indicate the clinical value o...Continue Reading

Citations

Oct 6, 2000·Pediatric Neurology·S P MillerA M O'Gorman
Jan 22, 1998·Pediatric Neurology·G CioniJ van Hof-van Duin
Sep 12, 2009·Journal of Child Neurology·Fadoua Saadani-MakkiDiane Chugani
Oct 14, 2009·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Sebastian GruntR Jeroen Vermeulen
Aug 2, 2011·Annual Review of Genomics and Human Genetics·Christian P SchaafArthur L Beaudet
Mar 30, 2011·Advances in Medical Sciences·W KułakB Kubas
Mar 9, 2011·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·Maxime DelcourJacques-Olivier Coq
Jan 30, 2010·Seminars in Perinatology·Sujatha Kannan, Harry T Chugani
May 4, 2005·Pediatric Neurology·Wojciech KulakJerzy Walecki
Jan 27, 2007·Developmental Medicine and Child Neurology·Ingeborg Krägeloh-Mann, Veronka Horber
Jun 27, 2015·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·Joke J GeytenbeekR Jeroen Vermeulen
May 16, 2015·Current Opinion in Neurobiology·Robert M BrownstoneNicolas Stifani
Jul 5, 2007·Journal of Child Neurology·Wojciech KułakKrzysztof Sendrowski
Apr 6, 2021·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·Irene MollR Jeroen Vermeulen

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